3-Amino-5-chloro-2-hydroxybenzoic acid

Base Information

Chemical Name:3-Amino-5-chloro-2-hydroxybenzoic acid
CAS No.:7180-80-5
Molecular Formula:C7H6ClNO3
Molecular Weight:187.583
Hs Code.:
DSSTox Substance ID:DTXSID50607760
Nikkaji Number:J81.347H
Wikidata:Q82506838
Mol file:7180-80-5.mol

Synonyms:3-Amino-5-chloro-2-hydroxybenzoic acid;7180-80-5;SCHEMBL1549305;DTXSID50607760;STL196746;AKOS016035902;CS-0267968;EN300-72855;F83409;AP-970/43483520

Suppliers and Price of 3-Amino-5-chloro-2-hydroxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
3-Amino-5-chloro-2-hydroxy-benzoicacid 95%
2.5 G
$ 990.00

Chemcia Scientific
3-Amino-5-chloro-2-hydroxy-benzoicacid 95%
0.5 G
$ 335.00

Total 4 raw suppliers

Chemical Property of 3-Amino-5-chloro-2-hydroxybenzoic acid

Chemical Property:

PSA：83.55000
LogP:1.90720
XLogP3:1.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:187.0036207
Heavy Atom Count:12
Complexity:188

Purity/Quality:

99% ^*data from raw suppliers

3-Amino-5-chloro-2-hydroxy-benzoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1C(=O)O)O)N)Cl

Technology Process of 3-Amino-5-chloro-2-hydroxybenzoic acid

There total 3 articles about 3-Amino-5-chloro-2-hydroxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 7195-78-0
5-chloro-2-hydroxy-3-nitrobenzoic acid

: 7180-80-5
3-amino-5-chloro-2-hydroxybenzoic acid

Guidance literature:: With sodium dithionite; water; In methanol;
DOI:10.1007/s00044-015-1325-9

Reference yield:

: 321-14-2
5-chloro-2-hydroxybenzoic acid

: 7180-80-5
3-amino-5-chloro-2-hydroxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid; sulfuric acid / 20 °C

2: sodium dithionite; water / methanol

With sodium dithionite; sulfuric acid; water; nitric acid; In methanol;
DOI:10.1007/s00044-015-1325-9