2-(4-Fluorophenyl)pyrimidine

Base Information

Chemical Name:2-(4-Fluorophenyl)pyrimidine
CAS No.:68049-17-2
Molecular Formula:C10H7FN2
Molecular Weight:174.177
Hs Code.:
DSSTox Substance ID:DTXSID301304131
Nikkaji Number:J46.770G
Wikidata:Q63398218
Mol file:68049-17-2.mol

Synonyms:2-(4-Fluorophenyl)pyrimidine;68049-17-2;2-(p-fluorophenyl) pyrimidine;SCHEMBL2258014;DTXSID301304131;Pyrimidine, 2-(4-fluorophenyl)-;Q63398218

Suppliers and Price of 2-(4-Fluorophenyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-(4-Fluorophenyl)pyrimidine
1g
$ 2206.43

Alichem
2-(4-Fluorophenyl)pyrimidine
500mg
$ 1153.76

Alichem
2-(4-Fluorophenyl)pyrimidine
250mg
$ 849.59

Total 3 raw suppliers

Chemical Property of 2-(4-Fluorophenyl)pyrimidine

Chemical Property:

PSA：25.78000
LogP:2.28270
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:174.05932639
Heavy Atom Count:13
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Fluorophenyl)pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(N=C1)C2=CC=C(C=C2)F

Technology Process of 2-(4-Fluorophenyl)pyrimidine

There total 7 articles about 2-(4-Fluorophenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 456-14-4
4-fluorobenzamidine hydrochloride

: 289-96-3
1,2,3-triazine

: 68049-17-2
2-(4-fluorophenyl)-pyrimidine

Guidance literature:: 4-fluorobenzamidine hydrochloride; With potassium hydroxide;

1,2,3-triazine; In acetonitrile; at 60 ℃; for 2h; regioselective reaction;
DOI:10.1021/ol2007428

Reference yield: 99.0%

: 2339-59-5
4-fluorobenzamidine

: 289-96-3
1,2,3-triazine

: 68049-17-2
2-(4-fluorophenyl)-pyrimidine

Guidance literature:: In acetonitrile; at 25 - 60 ℃; for 2.08333h; regioselective reaction;
DOI:10.1021/ja204856a

Reference yield: 97.0%

: 1765-93-1
4-fluoroboronic acid

: 4595-60-2
2-bromopyrimidine

: 68049-17-2
2-(4-fluorophenyl)-pyrimidine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; water; at 70 ℃; for 8h;
DOI:10.1039/c4ta00613e