NQ301

Base Information

• Chemical Name: NQ301
• CAS No.: 130089-98-4
• Molecular Formula: C₁₈H₁₂ClNO₃
• Molecular Weight: 325.751
• Mol file: 130089-98-4.mol

Synonyms:NQ301

Chemical Property of NQ301

Chemical Property:

• Melting Point: 241-243 °C(Solv: ethanol (64-17-5))
• Boiling Point: 476.8±45.0 °C(Predicted)
• PKA: -5.25±0.20(Predicted)
• PSA: 0.00000
• Density: 1.40±0.1 g/cm3(Predicted)
• LogP: 0.00000
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

NQ301 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: NQ 301 possess antiplatelet effect, making it an antithrombotic agent. It significantly inhibited the collagen-?, thrombin-?, arachidonic acid-?, thapsigargin- and calcium ionophore A23187-?induced aggregation of washed human platelets.

Technology Process of NQ301

There total 2 articles about NQ301 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2,3-Dichloro-1,4-naphthoquinone (117-80-6) + p-aminobenzophenone (99-92-3) → NQ301 (130089-98-4)

Guidance literature:

In neat (no solvent, solid phase); at 40 ℃; for 1h;

DOI:10.1016/j.saa.2012.08.056

Reference yield:

→ NQ301 (130089-98-4)

Guidance literature:

upstream raw materials:

2,3-Dichloro-1,4-naphthoquinone

p-aminobenzophenone