2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol

Base Information

Chemical Name:2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol
CAS No.:1207746-99-3
Molecular Formula:C17H15FN2O2
Molecular Weight:298.317
Hs Code.:
Mol file:1207746-99-3.mol

Synonyms:2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

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Hazard Codes:

MSDS Files:: SDS file from LookChem

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Technology Process of 2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol

There total 2 articles about 2-(5-(2-(4-fluorophenyl)oxazol-4-yl)pyridin-2-yl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 897027-51-9
2-(4-fluorophenyl)-1,3-oxazol-4-yl trifluoromethanesulfonate

: 290307-40-3
2-(5-bromopyridin-2-yl)propan-2-ol

: 1207746-99-3
2-{5-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]pyridin-2-yl}propan-2-ol

Guidance literature:: 2-(4-fluorophenyl)-1,3-oxazol-4-yl trifluoromethanesulfonate; With 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; bis(pinacol)diborane; In 1,4-dioxane; at 101 ℃; for 3h;

2-(5-bromopyridin-2-yl)propan-2-ol; With trans-bis(triphenylphosphine)palladium dichloride; sodium carbonate; In 1,4-dioxane; water; at 65 - 91 ℃; for 12h; Reagent/catalyst;
DOI:10.1021/ml5001239

Reference yield:

: 897027-51-9
2-(4-fluorophenyl)-1,3-oxazol-4-yl trifluoromethanesulfonate

: 73183-34-3
bis(pinacol)diborane

: 290307-40-3
2-(5-bromopyridin-2-yl)propan-2-ol

: 1207746-99-3
2-{5-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]pyridin-2-yl}propan-2-ol

Guidance literature:: 2-(4-fluorophenyl)-1,3-oxazol-4-yl trifluoromethanesulfonate; bis(pinacol)diborane; With potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 101 ℃; for 3h;

2-(5-bromopyridin-2-yl)propan-2-ol; With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; water; at 65 - 91 ℃;