(4-Bromophenyl)(4-methylphenyl)methanol

Base Information

• Chemical Name: (4-Bromophenyl)(4-methylphenyl)methanol
• CAS No.: 29334-17-6
• Molecular Formula: C14H13BrO
• Molecular Weight: 277.161
• Hs Code.: 2906299090
• DSSTox Substance ID: DTXSID30471840
• Nikkaji Number: J2.971.986A
• Mol file: 29334-17-6.mol

Synonyms:(4-Bromophenyl)(4-methylphenyl)methanol;29334-17-6;(4-bromophenyl)-(4-methylphenyl)methanol;4-Bromo-4'-methylbenzhydrol;SCHEMBL5351433;DTXSID30471840;(4-Bromophenyl)(p-tolyl)methanol;OZBSVWMYQPYYSC-UHFFFAOYSA-N;MFCD11096330;AKOS003583198;(4'-bromophenyl)-4-methylphenyl methanol;BS-22237;CS-0210014;Benzenemethanol, 4-bromo-alpha-(4-methylphenyl)-

Chemical Property of (4-Bromophenyl)(4-methylphenyl)methanol

Chemical Property:

• PSA: 20.23000
• LogP: 3.83920
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 276.01498
• Heavy Atom Count: 16
• Complexity: 203

Purity/Quality:

99% ^*data from raw suppliers

(4-Bromophenyl)(4-methylphenyl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C(C2=CC=C(C=C2)Br)O

Technology Process of (4-Bromophenyl)(4-methylphenyl)methanol

There total 4 articles about (4-Bromophenyl)(4-methylphenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

tri(4-tolyl)boroxine (5084-80-0) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromophenyl)(4-methylphenyl)methanol (29334-17-6)

Guidance literature:

With C₄₂H₆₂ClO₃PPd; sodium phosphate; In toluene; at 50 ℃; for 36h;

DOI:10.1016/j.tetlet.2011.04.074

Reference yield: 82.0%

4-methylphenylboronic acid (5720-05-8) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromophenyl)(4-methylphenyl)methanol (29334-17-6)

Guidance literature:

With potassium phosphate; platinacycle; In toluene; at 60 - 80 ℃;

DOI:10.1021/ol800774c

Reference yield: 62.0%

para-bromotoluene (106-38-7) + 4-bromo-benzaldehyde (1122-91-4) → (4-bromophenyl)(4-methylphenyl)methanol (29334-17-6)

Guidance literature:

para-bromotoluene; With magnesium; In diethyl ether; Heating;

4-bromo-benzaldehyde; In diethyl ether; for 0.5h; Heating;

DOI:10.1562/0031-8655(2002)076<0135:NPFMET>2.0.CO;2

upstream raw materials:

para-bromotoluene

4-bromo-benzaldehyde

4-methylphenylboronic acid

tri(4-tolyl)boroxine

Downstream raw materials:

4-Methyl-4'-brom-diphenyl-brommethan

C₃₅H₃₄N₂O₆

methyl 4-(4-bromobenzoyl)benzoate

4-(4'-bromobenzoyl)benzoic acid

Refernces

• 1、 Jana, Ranjan,Tunge, Jon A.. "A homogeneous, recyclable polymer support for rh(I)-catalyzed c-c bond formation". experimental part. p. 8376 - 8385. Retrieved 2011/12/04.
• 2、 Liao, Yuan-Xi,Xing, Chun-Hui,He, Ping,Hu, Qiao-Sheng. "Orthoplatinated triarylphosphite as a highly efficient catalyst for addition reactions of arylboronic acids with aldehydes: Low catalyst loading catalysis and a new tandem reaction sequence". supporting information; experimental part. p. 2509 - 2512. Retrieved 2009/05/26.