Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy

Base Information

Chemical Name:Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy
CAS No.:195005-73-3
Molecular Formula:C14H18INO5
Molecular Weight:407.205
Hs Code.:
Mol file:195005-73-3.mol

Synonyms:Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy

Suppliers and Price of Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy

Chemical Property:

PSA：84.86000
LogP:3.34110

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy

There total 4 articles about Benzeneacetic acid,a-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-iodo-4-Methoxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 218912-19-7
N-(tert-butyloxycarbonyl)-D-(3-iodo-4-methoxyphenyl)glycine methyl ester

: 195005-73-3
(R)-tert-Butoxycarbonylamino-(3-iodo-4-methoxy-phenyl)-acetic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 0.5h;
DOI:10.1016/j.tetlet.2017.10.046

Reference yield:

: 193073-85-7
methyl (R)-2-((tert-butoxycarbonyl)amino)-2-(4-methoxyphenyl)acetate

: 195005-73-3
(R)-tert-Butoxycarbonylamino-(3-iodo-4-methoxy-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: silver trifluoroacetate; iodine / chloroform / 20 h / 20 °C

2: lithium hydroxide monohydrate / water; tetrahydrofuran / 0.5 h / 20 °C

With lithium hydroxide monohydrate; iodine; silver trifluoroacetate; In tetrahydrofuran; chloroform; water;
DOI:10.1016/j.tetlet.2017.10.046

Reference yield:

: 27460-85-1
N-(tert-butoxycarbonyl)-D-(4-hydroxyphenyl)glycine

: 195005-73-3
(R)-tert-Butoxycarbonylamino-(3-iodo-4-methoxy-phenyl)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 1.5 h / 20 °C

2: silver trifluoroacetate; iodine / chloroform / 20 h / 20 °C

3: lithium hydroxide monohydrate / water; tetrahydrofuran / 0.5 h / 20 °C

With lithium hydroxide monohydrate; iodine; silver trifluoroacetate; potassium carbonate; In tetrahydrofuran; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2017.10.046