tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate
CAS No.:301221-81-8
Molecular Formula:C₂₀H₂₇N₃O₂
Molecular Weight:341.453
Hs Code.:
Mol file:301221-81-8.mol

Synonyms:tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate

Suppliers and Price of tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate

There total 4 articles about tert-butyl 4-(2-benzyl-1H-imidazol-5-yl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139290-70-3
tert-butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylate

: 301221-81-8
4-(2-benzyl-3H-imidazol-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: diethyl ether

2.1: LDA; TMSCl

2.2: NBS

3.1: CHCl₃ / Heating

4.1: ammonium formate; aq. AcOH; Pd/C

With palladium on activated charcoal; chloro-trimethyl-silane; ammonium formate; acetic acid; lithium diisopropyl amide; In diethyl ether; chloroform;
DOI:10.1016/j.bmcl.2004.04.078

Reference yield:

: 206989-61-9
4-acetyl-1-(t-butoxycarbonyl)piperidine

: 301221-81-8
4-(2-benzyl-3H-imidazol-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: LDA; TMSCl

1.2: NBS

2.1: CHCl₃ / Heating

3.1: ammonium formate; aq. AcOH; Pd/C

With palladium on activated charcoal; chloro-trimethyl-silane; ammonium formate; acetic acid; lithium diisopropyl amide; In chloroform;
DOI:10.1016/j.bmcl.2004.04.078

Reference yield:

: 301221-79-4
4-Bromoacetyl-1-(t-butoxycarbonyl)piperidine

: 301221-81-8
4-(2-benzyl-3H-imidazol-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: CHCl₃ / Heating

2: ammonium formate; aq. AcOH; Pd/C

With palladium on activated charcoal; ammonium formate; acetic acid; In chloroform;
DOI:10.1016/j.bmcl.2004.04.078