1-(3,4-Difluorophenyl)propan-2-amine

Base Information

Chemical Name:1-(3,4-Difluorophenyl)propan-2-amine
CAS No.:31338-32-6
Molecular Formula:C9H11F2N
Molecular Weight:171.19
Hs Code.:2921499090
DSSTox Substance ID:DTXSID80457891
Mol file:31338-32-6.mol

Synonyms:1-(3,4-difluorophenyl)propan-2-amine;31338-32-6;1-(3,4-Difluorophenyl)-2-aminopropane;SCHEMBL1179502;DTXSID80457891;GJEXOPSQWJWJRQ-UHFFFAOYSA-N;AKOS000159295;AKOS022488554;N11068

Suppliers and Price of 1-(3,4-Difluorophenyl)propan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3,4-DIFLUOROPHENYL)-2-AMINOPROPANE 95.00%
5MG
$ 497.07

AccelPharmtech
1-(3,4-difluorophenyl)propan-2-amine 97.00%
25G
$ 4010.00

AccelPharmtech
1-(3,4-difluorophenyl)propan-2-amine 97.00%
5G
$ 2180.00

AccelPharmtech
1-(3,4-difluorophenyl)propan-2-amine 97.00%
1G
$ 1940.00

Total 10 raw suppliers

Chemical Property of 1-(3,4-Difluorophenyl)propan-2-amine

Chemical Property:

Boiling Point:215.2±25.0 °C(Predicted)
PKA:9.29±0.10(Predicted)
PSA：26.02000
Density:1.131±0.06 g/cm3(Predicted)
LogP:2.55480
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:171.08595568
Heavy Atom Count:12
Complexity:141

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

1-(3,4-DIFLUOROPHENYL)-2-AMINOPROPANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1)F)F)N

Technology Process of 1-(3,4-Difluorophenyl)propan-2-amine

There total 3 articles about 1-(3,4-Difluorophenyl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-(3,4-difluorophenyl)-2-nitropropene

: 31338-32-6
1-(3,4-difluorophenyl)propan-2-amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Heating;
DOI:10.1021/jm0401356

Reference yield:

: 34036-07-2
3,4 difluorobenzaldehyde

: 31338-32-6
1-(3,4-difluorophenyl)propan-2-amine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / 3 h / Heating

2: 7.78 g / LiAlH₄ / tetrahydrofuran / 1 h / Heating

With ammonium acetate; lithium aluminium tetrahydride; In tetrahydrofuran; 1: Henry condensation;
DOI:10.1021/jm0401356