4-broMo-2-fluoro-6-Methoxyaniline HBr

Base Information

• Chemical Name: 4-broMo-2-fluoro-6-Methoxyaniline HBr
• CAS No.: 1261216-27-6
• Molecular Formula: C7H7BrFNO
• Molecular Weight: 220.041
• Hs Code.: 2921420090
• Mol file: 1261216-27-6.mol

Synonyms:4-broMo-2-fluoro-6-Methoxyaniline HBr;4-broMo-2-fluoro-6-Methoxyaniline

Chemical Property of 4-broMo-2-fluoro-6-Methoxyaniline HBr

Chemical Property:

• PSA: 35.25000
• LogP: 2.76020

Purity/Quality:

95+% ^*data from raw suppliers

4-Bromo-2-fluoro-6-methoxyaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 4-broMo-2-fluoro-6-Methoxyaniline HBr

There total 1 articles about 4-broMo-2-fluoro-6-Methoxyaniline HBr which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.4%

2-fluoro-6-methoxyphenylamine (446-61-7) → 4-bromo-2- fluoro-6-methoxyaniline (1261216-27-6)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 30 ℃; for 2h;

Reference yield: 89.22%

4-bromo-2- fluoro-6-methoxyaniline (1261216-27-6) + sodium methansulfinate (20277-69-4) → 2-fluoro-6-methoxy-4-(methylsulfonyl)aniline

Guidance literature:

With copper(l) iodide; rac-Pro-OH; sodium hydroxide; In dimethyl sulfoxide; at 90 ℃; for 16h; Inert atmosphere;

Reference yield: 81.6%

4-bromo-2- fluoro-6-methoxyaniline (1261216-27-6) → 2-amino-5-bromo-3-fluorophenol (186309-73-9)

Guidance literature:

With boron tribromide; In dichloromethane; at 0 ℃; for 1h;

upstream raw materials:

2-fluoro-6-methoxyphenylamine

Downstream raw materials:

2-amino-5-bromo-3-fluorophenol

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