8-Iodonaphthalene-1-carboxaldehyde

Base Information

Chemical Name:8-Iodonaphthalene-1-carboxaldehyde
CAS No.:85864-86-4
Molecular Formula:C11H7IO
Molecular Weight:282.08
Hs Code.:
DSSTox Substance ID:DTXSID00463116
Nikkaji Number:J3.559.087K
Wikidata:Q82287899
Mol file:85864-86-4.mol

Synonyms:8-Iodonaphthalene-1-carboxaldehyde;85864-86-4;DTXSID00463116;FT-0769754

Suppliers and Price of 8-Iodonaphthalene-1-carboxaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
8-Iodonaphthalene-1-carboxaldehyde
500mg
$ 970.20

Total 4 raw suppliers

Chemical Property of 8-Iodonaphthalene-1-carboxaldehyde

Chemical Property:

Melting Point:81-82 °C
Boiling Point:378.5±15.0 °C(Predicted)
PSA：17.07000
Density:1.793±0.06 g/cm3(Predicted)
LogP:3.25690
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:281.95416
Heavy Atom Count:13
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

8-Iodonaphthalene-1-carboxaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)C=O)C(=CC=C2)I

Technology Process of 8-Iodonaphthalene-1-carboxaldehyde

There total 4 articles about 8-Iodonaphthalene-1-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1730-04-7
1,8-diiodonaphthalene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 85864-86-4
8-iodonaphthalene-1-carbaldehyde

Guidance literature:: 1,8-diiodonaphthalene; With n-butyllithium; In diethyl ether; hexane; at -78 - -30 ℃; for 2h; Inert atmosphere;

N,N-dimethyl-formamide; In diethyl ether; hexane; at -78 - -30 ℃; for 16h; Inert atmosphere;
DOI:10.1002/chem.201303826

Reference yield:

: 85864-84-2
(8-iodonaphthalen-1-yl)methanol

: 85864-86-4
8-iodonaphthalene-1-carbaldehyde

Guidance literature:: With N-chloro-succinimide; dimethylsulfide; triethylamine; In toluene; at -20 ℃;
DOI:10.1021/ja00357a021

Reference yield:

: 479-27-6
naphthalene-1,8-diamine

: 85864-86-4
8-iodonaphthalene-1-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: sulfuric acid; sodium nitrite / water / 0.67 h / -20 °C

1.2: 30 h / -20 - 40 °C

2.1: n-butyllithium / hexane; diethyl ether / 2 h / -78 - -30 °C / Inert atmosphere

2.2: 16 h / -78 - -30 °C / Inert atmosphere

With n-butyllithium; sulfuric acid; sodium nitrite; In diethyl ether; hexane; water;
DOI:10.1002/chem.201303826