N-benzyl-4-chloro-3-nitrobenzamide

Base Information

• Chemical Name: N-benzyl-4-chloro-3-nitrobenzamide
• CAS No.: 92102-83-5
• Molecular Formula: C14H11ClN2O3
• Molecular Weight: 290.706
• Mol file: 92102-83-5.mol

Synonyms:N-benzyl-4-chloro-3-nitrobenzamide

Chemical Property of N-benzyl-4-chloro-3-nitrobenzamide

Chemical Property:

• Vapor Pressure: 5.04E-09mmHg at 25°C
• Boiling Point: 470.5°C at 760 mmHg
• Flash Point: 238.3°C
• PSA: 74.92000
• Density: 1.356g/cm³
• LogP: 4.09230

Purity/Quality:

99% ^*data from raw suppliers

N-BENZYL-4-CHLORO-3-NITROBENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-benzyl-4-chloro-3-nitrobenzamide

There total 2 articles about N-benzyl-4-chloro-3-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.7%

benzylamine (100-46-9) + 4-chloro-3-nitro-benzoyl chloride (38818-50-7) → benzyl 4-chloro-3-nitro-benzamide (92102-83-5)

Guidance literature:

With triethylamine; dmap; In diethyl ether; at 20 ℃; for 18h;

Reference yield:

→ benzyl 4-chloro-3-nitro-benzamide (92102-83-5)

Guidance literature:

4-Chlor-3-nitrobenzoylchlorid, Benzylamin;

Reference yield: 89.7%

benzyl 4-chloro-3-nitro-benzamide (92102-83-5) → 3-amino-N-benzyl-4-chloro-benzamide

Guidance literature:

benzyl 4-chloro-3-nitro-benzamide; With iron; acetic acid; In ethanol; water; at 100 ℃; for 0.5h;

With ammonium hydroxide; In ethanol; water; ethyl acetate; Cooling with ice;

upstream raw materials:

benzylamine

4-chloro-3-nitro-benzoyl chloride

Downstream raw materials:

2-Methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (5-benzylcarbamoyl-2-chloro-phenyl)-amide

2-(4-methyl-piperazin-1-yl)-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (5-benzylcarbamoyl-2-chloro-phenyl)-amide

N-(5-benzylcarbamoyl-2-chloro-phenyl)-malonamic acid methyl ester

Refernces

• 1、 -. "PYRIDO PYRIMIDINES". Page/Page column 12. . Retrieved 2012/07/28.