ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate

Base Information

• Chemical Name: ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate
• CAS No.: 54368-62-6
• Molecular Formula: C₇H₇Cl₂N₃O₂
• Molecular Weight: 236.057
• Hs Code.: 2933599090
• Mol file: 54368-62-6.mol

Synonyms:ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate;5-AMino-2,6-dichloro-pyriMidine-4-carboxylic acid ethyl ester;5-Amino-2,6-dichloro-4-pyrimidinecarboxylic acid ethyl ester

Chemical Property of ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate

Chemical Property:

• Boiling Point: 358.0±37.0 °C(Predicted)
• PKA: -4.07±0.10(Predicted)
• PSA: 78.10000
• Density: 1.508±0.06 g/cm3(Predicted)
• LogP: 2.12350
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl5-amino-2,6-dichloropyrimidine-4-carboxylate ^*data from reagent suppliers

Safty Information:

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MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate

There total 2 articles about ethyl 5-aMino-2,6-dichloropyriMidine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

ethyl 2,4-dichloro-5-nitro-6-pyrimidinecarboxylic acid (54368-61-5) → ethyl 5-amino-2,6-dichloropyrimidine-4-carboxylate (54368-62-6)

Guidance literature:

With tin(II) chloride dihdyrate; In ethyl acetate; at 70 ℃; for 5h; Time; Sealed tube;

Reference yield:

→ ethyl 5-amino-2,6-dichloropyrimidine-4-carboxylate (54368-62-6)

Guidance literature:

aus dem entspr. 5-Nitropyrimidincarboxylat;

upstream raw materials:

ethyl 2,4-dichloro-5-nitro-6-pyrimidinecarboxylic acid

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