2-Chloro-N-(2,4-dimethylphenyl)acetamide

Base Information

Chemical Name:2-Chloro-N-(2,4-dimethylphenyl)acetamide
CAS No.:39106-10-0
Molecular Formula:C10H12 Cl N O
Molecular Weight:197.664
Hs Code.:2924299090
European Community (EC) Number:254-294-2
DSSTox Substance ID:DTXSID0068157
Nikkaji Number:J261.310G
Wikidata:Q81994869
ChEMBL ID:CHEMBL1342703
Mol file:39106-10-0.mol

Synonyms:2-Chloro-N-(2,4-dimethylphenyl)acetamide;39106-10-0;Acetamide, 2-chloro-N-(2,4-dimethylphenyl)-;2-Chloro-N-(2,4-dimethyl-phenyl)-acetamide;N-(2,4-dimethylphenyl)-2-chloroacetamide;EINECS 254-294-2;MLS001004621;SCHEMBL4228749;CHEMBL1342703;DTXSID0068157;HMS2674D24;MFCD00464946;STK115105;AKOS000266640;N-(Chloroacetyl) 2,4-dimethylaniline;Chloro-N-(2,4-dimethylphenyl)acetamide;NCGC00246018-01;3-(4-CHLOROPHENYLTHIO)BUTYRICACID;BS-10271;SMR000348196;BB 0243203;CS-0116496;EN300-01666;D93444;Z56786856;F0807-0509

Suppliers and Price of 2-Chloro-N-(2,4-dimethylphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2,4-Dimethylphenyl)-2-chloroacetamide
500mg
$ 120.00

Medical Isotopes, Inc.
N-(2,4-Dimethylphenyl)-2-chloroacetamide
500 mg
$ 625.00

Medical Isotopes, Inc.
N-(2,4-Dimethylphenyl)-2-chloroacetamide
10 g
$ 2425.00

Matrix Scientific
2-Chloro-N-(2,4-dimethylphenyl)acetamide
500mg
$ 95.00

Heterocyclics
2-Chloro-N-(2,4-dimethylphenyl)acetamide 97%
1g
$ 118.00

Heterocyclics
2-Chloro-N-(2,4-dimethylphenyl)acetamide 97%
5g
$ 366.00

Crysdot
2-Chloro-N-(2,4-dimethylphenyl)acetamide 95+%
10g
$ 942.00

Crysdot
2-Chloro-N-(2,4-dimethylphenyl)acetamide 95+%
5g
$ 658.00

Chemenu
2-chloro-N-(2,4-dimethylphenyl)acetamide 95%
10g
$ 336.00

Chemenu
2-chloro-N-(2,4-dimethylphenyl)acetamide 95%
5g
$ 228.00

Total 16 raw suppliers

Chemical Property of 2-Chloro-N-(2,4-dimethylphenyl)acetamide

Chemical Property:

Vapor Pressure:0.000159mmHg at 25°C
Melting Point:144-146 °C(Solv: ethanol (64-17-5))
Boiling Point:331.1°Cat760mmHg
PKA:12.91±0.70(Predicted)
Flash Point:154.1°C
PSA：29.10000
Density:1.187g/cm³
LogP:2.55370
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:197.0607417
Heavy Atom Count:13
Complexity:184

Purity/Quality:

99%, ^*data from raw suppliers

N-(2,4-Dimethylphenyl)-2-chloroacetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)NC(=O)CCl)C
Uses N-(2,4-Dimethylphenyl)-2-chloroacetamide is an intermediate in the synthesis of Tetrahydrophthalimide derivative as inhibitors of HIV-1 reverse transcriptase.

Technology Process of 2-Chloro-N-(2,4-dimethylphenyl)acetamide

There total 1 articles about 2-Chloro-N-(2,4-dimethylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 79-04-9
chloroacetyl chloride

: 95-68-1
2,4-Xylidine

: 39106-10-0
2-chloro-N-(2,4-dimethylphenyl)acetamide

Guidance literature:: In 1,4-dioxane; at 20 ℃; for 1h; Heating / reflux;

Reference yield: 91.0%

: 39106-10-0
2-chloro-N-(2,4-dimethylphenyl)acetamide

: 97963-62-7
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

: 2-(5-difluoromethoxy-1H-benzoimidazol-2-ylsulfanyl)-N-(2,4-dimethylphenyl)acetamide

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 4h;
DOI:10.14233/ajchem.2021.23174

Reference yield: 88.0%

: 39106-10-0
2-chloro-N-(2,4-dimethylphenyl)acetamide

: 5-(chloromethyl)-1-(2,4-dimethylphenyl)-1H-tetrazole

Guidance literature:: 2-chloro-N-(2,4-dimethylphenyl)acetamide; With phosphorus pentachloride; In benzene; at 50 - 60 ℃;

With hydrogen azide; In benzene; at 5 - 10 ℃; for 1h; Inert atmosphere; Reflux;
DOI:10.1007/s10593-019-02533-2