4-(3-(Methylsulfonyl)phenyl)piperidine

Base Information

Chemical Name:4-(3-(Methylsulfonyl)phenyl)piperidine
CAS No.:346688-72-0
Molecular Formula:C12H17NO2S
Molecular Weight:239.338
Hs Code.:
DSSTox Substance ID:DTXSID60514451
Wikidata:Q82374789
Mol file:346688-72-0.mol

Synonyms:4-(3-(Methylsulfonyl)phenyl)piperidine;346688-72-0;4-(3-methylsulfonylphenyl)piperidine;SCHEMBL169132;DTXSID60514451;BFFDEVPWGSZYSN-UHFFFAOYSA-N;4-(3-methanesulfonyl-phenyl)piperidine;SB43865;4-(3-methanesulfonyl-phenyl)-piperidine;4-[3-(Methanesulfonyl)phenyl]piperidine;4-(3-METHANESULFONYLPHENYL)PIPERIDINE;FT-0735070;EN300-1987684

Suppliers and Price of 4-(3-(Methylsulfonyl)phenyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(3-(Methylsulfonyl)phenyl)piperidine 95+%
1g
$ 541.00

Crysdot
4-(3-(Methylsulfonyl)phenyl)piperidine 95+%
5g
$ 1409.00

Chemenu
4-(3-(methylsulfonyl)phenyl)piperidine 95%
5g
$ 1328.00

Chemenu
4-(3-(methylsulfonyl)phenyl)piperidine 95%
1g
$ 511.00

Alichem
4-(3-(Methylsulfonyl)phenyl)piperidine
25g
$ 4877.60

Alichem
4-(3-(Methylsulfonyl)phenyl)piperidine
10g
$ 2508.48

Alichem
4-(3-(Methylsulfonyl)phenyl)piperidine
5g
$ 1752.72

Total 2 raw suppliers

Chemical Property of 4-(3-(Methylsulfonyl)phenyl)piperidine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:425.343°C at 760 mmHg
PKA:10.05±0.10(Predicted)
Flash Point:211.04°C
PSA：54.55000
Density:1.148g/cm³
LogP:2.96670
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:239.09799996
Heavy Atom Count:16
Complexity:314

Purity/Quality:

95+% ^*data from raw suppliers

4-(3-(Methylsulfonyl)phenyl)piperidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)C1=CC=CC(=C1)C2CCNCC2

Technology Process of 4-(3-(Methylsulfonyl)phenyl)piperidine

There total 4 articles about 4-(3-(Methylsulfonyl)phenyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: tert-butyl 4-(3-(methylsulfonyl)phenyl)piperidine-1-carboxylate

: 346688-72-0
ACR₃₀

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 18 ℃; for 4h; Inert atmosphere;
DOI:10.1039/c7cc08670a

Reference yield: 86.0%

: 346688-71-9
1-methoxycarbonyl-4-[3-(methylsulfonyl)phenyl]piperidine

: 346688-72-0
ACR₃₀

Guidance literature:: 1-methoxycarbonyl-4-[3-(methylsulfonyl)phenyl]piperidine; With hydrogenchloride; water; In ethanol; for 24h; Reflux;

With sodium hydroxide; In water;
DOI:10.1021/jm901689v

Reference yield:

: 34896-80-5
1-bromo-3-methanesulphonylbenzene

: 346688-72-0
ACR₃₀

Guidance literature:: Multi-step reaction with 2 steps

1.1: chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); palladium 10% on activated carbon; potassium phosphate / 1,4-dioxane; water / 4 h / 80 °C / Sealed tube; Inert atmosphere

1.2: 16 h / 18 °C

2.1: trifluoroacetic acid / dichloromethane / 4 h / 18 °C / Inert atmosphere

With potassium phosphate; chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II); palladium 10% on activated carbon; trifluoroacetic acid; In 1,4-dioxane; dichloromethane; water;
DOI:10.1039/c7cc08670a