ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Base Information

Chemical Name:ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate
CAS No.:913558-33-5
Molecular Formula:C10H12N2O3
Molecular Weight:208.21
Hs Code.:
Mol file:913558-33-5.mol

Synonyms:ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate;Ethyl 5-oxo-4,5,6,7-H4-indazole-3-carboxylate

Suppliers and Price of ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate AldrichCPR
250mg
$ 140.00

Acrotein
Ethyl5-oxo-4,5,6,7-H4-indazole-3-carboxylate 97%
0.25g
$ 302.50

Total 4 raw suppliers

Chemical Property of ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Chemical Property:

PSA：72.05000
LogP:0.64420

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

There total 3 articles about ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 913558-29-9
ethyl 1,4,6,7-tetrahydrospiro[indazole-5,2′-[1,3]dioxolane]-3-carboxylate

: 913558-33-5
ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Guidance literature:: With hydrogenchloride; water; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmcl.2009.06.054

Reference yield:

: 913558-25-5
ethyl 2-(8-hydroxy-1,4-dioxaspiro[4.5]dec-7-en-7-yl)-2-oxoacetate

: 913558-33-5
ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; hydrazine / ethanol; water / 1.5 h / 65 °C

2: hydrogenchloride / tetrahydrofuran; ethanol; water / 48 h / 60 °C

With hydrogenchloride; acetic acid; hydrazine; In tetrahydrofuran; ethanol; water;

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 913558-33-5
ethyl 5-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium tert-butylate / ethanol / 4 h / 20 °C

1.2: 16 h / 20 °C

2.1: pyridinium p-toluenesulfonate / water; acetone / 48 h / 65 °C

With potassium tert-butylate; pyridinium p-toluenesulfonate; In ethanol; water; acetone;