ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE

Base Information

Chemical Name:ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE
CAS No.:96259-44-8
Molecular Formula:C7H10N4O2S
Molecular Weight:214.24
Hs Code.:2933699090
Mol file:96259-44-8.mol

Synonyms:ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE

Suppliers and Price of ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE 95.00%
5MG
$ 505.56

Total 4 raw suppliers

Chemical Property of ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE

Chemical Property:

PSA：116.29000
LogP:0.93360

Purity/Quality:

98%min ^*data from raw suppliers

ETHYL-5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE

There total 5 articles about ETHYL 5-AMINO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 75824-03-2
5-chloro-3-methylsulfanyl-1,2,4-triazine-6-carboxylic acid ethyl ester

: 96259-44-8
ethyl 5-amino-3-(methylsulfanyl)-1,2,4-triazine-6-carboxylate

Guidance literature:: With ammonia; In ethanol; for 0.5h;
DOI:10.1021/jo00213a019

Reference yield:

: 31143-85-8
ethyl 3-(methylthio)-5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxylate

: 96259-44-8
ethyl 5-amino-3-(methylsulfanyl)-1,2,4-triazine-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 4 h / Reflux

2: ammonium hydroxide / 1,4-dioxane / 0.17 h / 20 °C

With ammonium hydroxide; thionyl chloride; In 1,4-dioxane;

Reference yield:

: 609-09-6
Diethyl ketomalonate

: 96259-44-8
ethyl 5-amino-3-(methylsulfanyl)-1,2,4-triazine-6-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride / ethanol; water / 2 h / 50 - 55 °C

1.2: 40 °C

2.1: potassium carbonate / DMF (N,N-dimethyl-formamide) / 0 - 20 °C

3.1: thionyl chloride / 2 h / 75 °C

4.1: ammonia / diethyl ether

With hydrogenchloride; thionyl chloride; ammonia; potassium carbonate; In DMF (N,N-dimethyl-formamide); diethyl ether; ethanol; water;