IDX-184

Base Information

Chemical Name:IDX-184
CAS No.:1036915-08-8
Molecular Formula:C25H35N6O9PS
Molecular Weight:626.627
Hs Code.:
Mol file:1036915-08-8.mol

Synonyms:IDX-184;2'-C-Methylguanosine 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl N-(phenylmethyl)phosphoramidate]

Suppliers and Price of IDX-184

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of IDX-184

Chemical Property:

Density:1.59

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of IDX-184

There total 5 articles about IDX-184 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1036915-07-7
2'-C-methylguanosine-5'-[2-[(3-trityloxy-2,2-dimethyl-1-oxopropyl)thio]ethyl-N-benzylphosphoramidate]

: 1036915-08-8
IDX 184

Guidance literature:: With ethanol; acetyl chloride; In acetonitrile; at 25 ℃; for 11.5h; Large scale;
DOI:10.1021/op5003837

Reference yield: 6.0%

: 1036915-08-8
IDX 184

Guidance literature:

Reference yield:

: 2'-C-methylguanosine-2',3'-O-phenylboronate

: 1036915-08-8
IDX 184

Guidance literature:: Multi-step reaction with 4 steps

1: pivaloyl chloride; pyridine / acetonitrile / 5 h / 8 - 17 °C / Large scale

2: tetrachloromethane / acetonitrile / 6 h / 8 - 10 °C / Large scale

3: citric acid / water; acetonitrile; tert-butyl methyl ether / 1 h / 25 °C / Large scale

4: acetyl chloride; ethanol / acetonitrile / 11.5 h / 25 °C / Large scale

With pyridine; tetrachloromethane; ethanol; pivaloyl chloride; acetyl chloride; citric acid; In tert-butyl methyl ether; water; acetonitrile; 2: |Atherton-Todd Synthesis;
DOI:10.1021/op5003837