5-(Benzyloxy)nicotinic acid

Base Information

Chemical Name:5-(Benzyloxy)nicotinic acid
CAS No.:263270-34-4
Molecular Formula:C13H11NO3
Molecular Weight:229.235
Hs Code.:
DSSTox Substance ID:DTXSID90593613
Wikidata:Q82488122
Mol file:263270-34-4.mol

Synonyms:5-(BENZYLOXY)NICOTINIC ACID;263270-34-4;5-(BENZYLOXY)PYRIDINE-3-CARBOXYLIC ACID;3-Pyridinecarboxylic acid, 5-(phenylmethoxy)-;5-Benzyloxynicotinic acid;5-benzyloxy-nicotinic acid;SCHEMBL1201866;DTXSID90593613;MWWYJDHPRJSMBL-UHFFFAOYSA-N;MFCD11845573;AKOS006298860;AB64588;5-phenylmethoxypyridine-3-carboxylic acid;BS-22164;DB-067608;CS-0195602;E90578

Suppliers and Price of 5-(Benzyloxy)nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AOBChem
5-(Benzyloxy)nicotinicacid 97%
10g
$ 2360.00

Total 4 raw suppliers

Chemical Property of 5-(Benzyloxy)nicotinic acid

Chemical Property:

PSA：59.42000
LogP:2.35880
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:229.07389321
Heavy Atom Count:17
Complexity:251

Purity/Quality:

98%min ^*data from raw suppliers

5-(Benzyloxy)nicotinicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CN=CC(=C2)C(=O)O

Technology Process of 5-(Benzyloxy)nicotinic acid

There total 5 articles about 5-(Benzyloxy)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 219817-42-2
methyl 5-(benzyloxy)nicotinate

: 263270-34-4
5-(benzyloxy)nicotinic acid

Guidance literature:: methyl 5-(benzyloxy)nicotinate; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 0.75h;

With hydrogenchloride; In water;

Reference yield:

: ethyl 5-(benzyloxy)nicotinate

: 263270-34-4
5-(benzyloxy)nicotinic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; ethanol; at 30 ℃;

Reference yield:

: 59288-38-9
ethyl 5-hydroxy-3-pyridinecarboxylate

: 263270-34-4
5-(benzyloxy)nicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: triphenylphosphine / tetrahydrofuran / 0.01 h / 0 °C

1.2: 0 - 20 °C

2.1: lithium hydroxide; water / ethanol; tetrahydrofuran / 30 °C

With water; triphenylphosphine; lithium hydroxide; In tetrahydrofuran; ethanol;