PH-THIO-BETA-D-GLCA

Base Information

• Chemical Name: PH-THIO-BETA-D-GLCA
• CAS No.: 26399-82-6
• Molecular Formula: C₁₂H₁₄O₆S
• Molecular Weight: 286.306
• Mol file: 26399-82-6.mol

Synonyms:PHENYL-BETA-D-THIOGLUCURONIC ACID;PHENYL-BETA-D-THIOGLUCURONIDE;PH-THIO-BETA-D-GLCA

Chemical Property of PH-THIO-BETA-D-GLCA

Chemical Property:

• PSA: 132.52000
• LogP: -0.32910

Purity/Quality:

98%Min ^*data from raw suppliers

BETA-D-GLUCOPYRANOSIDURONIC ACID, PHENYL 1-THIO- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PH-THIO-BETA-D-GLCA

There total 5 articles about PH-THIO-BETA-D-GLCA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiophenol (108-98-5) + baicalin (21967-41-9,27462-75-5,31564-28-0) → phenyl 1-thio-β-D-glucopyranosiduronic acid (26399-82-6)

Guidance literature:

With β-D-glucuronidase from Dictyoglomus thermophilum E396Q mutant; Cleland's reagent; In aq. phosphate buffer; at 37 ℃; for 24h; pH=5; Enzymatic reaction;

DOI:10.1039/d0ob00226g

Reference yield:

p-nitrophenyl-β-D-glucuronide (10344-94-2,60833-84-3) + thiophenol (108-98-5) → phenyl 1-thio-β-D-glucopyranosiduronic acid (26399-82-6)

Guidance literature:

With β-D-glucuronidase from Dictyoglomus thermophilum E396Q mutant; Cleland's reagent; In aq. phosphate buffer; at 37 ℃; for 24h; pH=5; Enzymatic reaction;

DOI:10.1039/d0ob00226g

Reference yield:

potassium thiophenolate (3111-52-2) → phenyl 1-thio-β-D-glucopyranosiduronic acid (26399-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol / Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin

With methanol;

upstream raw materials:

methyl (phenyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosid)uronate

potassium thiophenolate

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

thiophenol

Refernces