3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone

Base Information

Chemical Name:3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone
CAS No.:853192-45-7
Molecular Formula:C17H14BrNO2
Molecular Weight:344.2
Hs Code.:2933790090
DSSTox Substance ID:DTXSID20590837
Nikkaji Number:J2.158.172K
Wikidata:Q82484462
Mol file:853192-45-7.mol

Synonyms:853192-45-7;3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2 -quinolinone;3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone;3-bromo-4-(4-methoxyphenyl)-1-methyl-1h-quinolin-2-one;DTXSID20590837;SB72939;DB-315181;3-Bromo-4-(4-methoxyphenyl)-1-methylquinolin-2(1H)-one

Suppliers and Price of 3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone 95+%
1g
$ 761.00

Chemenu
3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone 95%
1g
$ 719.00

American Custom Chemicals Corporation
3-BROMO-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE 95.00%
1G
$ 1052.67

Total 1 raw suppliers

Chemical Property of 3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone

Chemical Property:

PSA：31.23000
LogP:3.97660
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:343.02079
Heavy Atom Count:21
Complexity:440

Purity/Quality:: 3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2C(=C(C1=O)Br)C3=CC=C(C=C3)OC

Technology Process of 3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone

There total 2 articles about 3-Bromo-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1677-46-9
4-hydroxy-1-methyl-2(1H)-quinolone

: 853192-45-7
3-bromo-4-(4-methoxyphenyl)-1-methylquinolin-2(1H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / NBS; Mg(ClO₄)2 / acetonitrile

2: 86 percent / Et₃N

3: 81 percent / Na₂CO₃ / PdCl₂(PPh₃)2 / tetrahydrofuran; H₂O / 20 °C

With N-Bromosuccinimide; magnesium(II) perchlorate; sodium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; acetonitrile; 3: Suzuki-Miyaura reaction;
DOI:10.1246/cl.2005.550

Reference yield:

: 90061-40-8
3-Brom-4-hydroxy-1-methyl-1,2-dihydrochinolin-2-on

: 853192-45-7
3-bromo-4-(4-methoxyphenyl)-1-methylquinolin-2(1H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / Et₃N

2: 81 percent / Na₂CO₃ / PdCl₂(PPh₃)2 / tetrahydrofuran; H₂O / 20 °C

With sodium carbonate; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; water; 2: Suzuki-Miyaura reaction;
DOI:10.1246/cl.2005.550

Reference yield:

: 853192-45-7
3-bromo-4-(4-methoxyphenyl)-1-methylquinolin-2(1H)-one

: 103529-16-4
2-[(trimethylsilyl)ethynyl]aniline

: 1010128-57-0
C₂₅H₂₀N₂O₂

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 50 ℃;
DOI:10.1016/j.tet.2007.12.003