4,4-Difluoro-L-proline Methyl ester trifluoroacetate

Base Information

Chemical Name:4,4-Difluoro-L-proline Methyl ester trifluoroacetate
CAS No.:915230-14-7
Molecular Formula:C8H10F5NO4
Molecular Weight:279.164
Hs Code.:
Mol file:915230-14-7.mol

Synonyms:4,4-Difluoro-L-proline Methyl ester trifluoroacetate;4,4-Difluoro-L-proline Me...;methyl (2S)-4,4-difluoropyrrolidine-2-carboxylate;(S)-Methyl 4,4-difluoropyrrolidine-2-carboxylate 2,2,2-trifluoroacetate

Suppliers and Price of 4,4-Difluoro-L-proline Methyl ester trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Methyl 4,4-Difluoro-L-proline trifluoroacetate
5 g
$ 750.00

SynQuest Laboratories
Methyl 4,4-Difluoro-L-proline trifluoroacetate
1 g
$ 225.00

Matrix Scientific
4,4-Difluoro-L-proline methyl ester trifluoroacetate
5g
$ 1300.00

Matrix Scientific
4,4-Difluoro-L-proline methyl ester trifluoroacetate
1g
$ 473.00

Crysdot
(S)-Methyl4,4-difluoropyrrolidine-2-carboxylate2,2,2-trifluoroacetate 95+%
5g
$ 667.00

Chemenu
methyl(2S)-4,4-difluoropyrrolidine-2-carboxylate;trifluoroaceticacid 95%+
10g
$ 792.00

Chemenu
methyl(2S)-4,4-difluoropyrrolidine-2-carboxylate;trifluoroaceticacid 95%+
5g
$ 484.00

Total 10 raw suppliers

Chemical Property of 4,4-Difluoro-L-proline Methyl ester trifluoroacetate

Chemical Property:

PSA：75.63000
LogP:1.11870

Purity/Quality:

97% ^*data from raw suppliers

Methyl 4,4-Difluoro-L-proline trifluoroacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4,4-Difluoro-L-proline Methyl ester trifluoroacetate

There total 5 articles about 4,4-Difluoro-L-proline Methyl ester trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 76-05-1
trifluoroacetic acid

: 203866-17-5
1-tert-butyl 2-methyl (2S)-4,4-difluoropyrrolidine-1,2-dicarboxylate

: 915230-14-7
(S)-methyl-4,4-difluoropyrrolidine-2-carboxylate trifluoroacetate

Guidance literature:: for 0.5h;

Reference yield:

: 647857-74-7
methyl (R)-1-tert-butoxycarbonyl-4,4-difluoropyrrolidine-2-carboxylate

: 76-05-1
trifluoroacetic acid

: 915230-14-7
(S)-methyl-4,4-difluoropyrrolidine-2-carboxylate trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 6h;

Reference yield:

: 102195-80-2
(S)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate

: 915230-14-7
(S)-methyl-4,4-difluoropyrrolidine-2-carboxylate trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: diethylamino-sulfur trifluoride / dichloromethane / 20 h / 0 - 20 °C

2: dichloromethane / 4 h / 20 °C

With diethylamino-sulfur trifluoride; In dichloromethane;
DOI:10.1021/acs.jmedchem.6b00879