203866-17-5

Basic information

• Product Name: BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER
• Synonyms: 1-tert-Butyl 2-methyl (S)-4,4-difluoropyrrolidine-1,2-dicarboxylate;Methyl (S)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate;Methyl (S)-1-Boc-4,4-difl...;1,2-Pyrrolidinedicarboxylicacid, 4,4-difluoro-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S)-;Methyl 1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-(2S)-carboxylate;N-Boc-4,4-Difluoro-L-proline Methyl ester 97%;1-tert-butyl 2-methyl (2S)-4,4-difluoropyrrolidine-1,2-dicarboxylate;N-Boc-4,4-Difluoro-L-proline methyl ester
• CAS NO: 203866-17-5
• Molecular Formula: C₁₁H₁₇F₂NO₄
• Molecular Weight: 265.25
• Mol File: 203866-17-5.mol
• Article Data: 35

Chemical Properties

• Melting Point: 41-46 °C
• Boiling Point: 293℃
• Flash Point: 110 °C
• Appearance: /
• Density: 1.22
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.455
• Storage Temp.: Store at 0-5°C
• PKA: -8.00±0.60(Predicted)
• CAS DataBase Reference: BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER(203866-17-5)
• EPA Substance Registry System: BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER(203866-17-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 203866-17-5(Hazardous Substances Data)

Usage

General Description

BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER is a chemical compound that is derived from proline, an amino acid commonly found in nature. The addition of two fluorine atoms to the proline molecule gives it unique properties and potential applications in medicinal chemistry. The compound is often used as a building block in the synthesis of pharmaceutical drugs and other bioactive molecules. Its methyl ester form allows for easier manipulation and handling in laboratory settings. Overall, BOC-4,4-DIFLUORO-L-PROLINE METHYL ESTER is a valuable chemical tool in the development of new drugs and biologically active compounds.

InChI:InChI=1/C11H17F2NO4/c1-10(2,3)18-9(16)14-6-11(12,13)5-7(14)8(15)17-4/h7H,5-6H2,1-4H3/t7-/m0/s1

Upstream product

• 40216-83-9 L-4-hydroxyproline methyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 102195-80-2 (S)-1-tert-butyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate 
• 203866-15-3 1-(tert-butoxycarbonyl)-4,4-difluoro-L-proline 
• 74-88-4 methyl iodide 
• 796095-60-8 (2S)-1-tert-butoxycarbonyl-2-(methoxycarbonyl)-4-hydroxyazacyclopentane 
• 1001383-50-1 trans-4-hydroxy-L-proline methyl ester 
• 51-35-4 4-hydroxyproline 
• 74844-91-0 (2S,4S)-N-tert-butoxycarbonyl-4-hydroxyproline methyl ester 
• 74844-91-0 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate 

Downstream Products

• 126111-14-6 methyl (2S)-4,4-difluoropyrrolidine-2-carboxylate 
• 203866-21-1 (2S)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4,4-difluoro-pyrrolidine-2-carboxylic acid 
• 915230-14-7 (S)-methyl-4,4-difluoropyrrolidine-2-carboxylate trifluoroacetate 
• 1021734-75-7 1-tert-butyl 2-methyl 2-(4-bromobenzyl)-4,4-difluoropyrrolidine-1,2-dicarboxylate 
• 426844-50-0 (S)-2-carbamoyl-4,4-difluoropyrrolidine-1-carboxylic acid tert-butyl ester 
• 1448440-48-9 (S)-tert-butyl 2-(2-carbamoyl-4,4-difluoropyrrolidin-1-yl)-2-oxoethylcarbamate 
• 1448440-50-3 tert-butyl (S)-(2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate 
• 1448440-51-4 (S)-1-(2-aminoacetyl)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride 
• 1414357-12-2 3-[(2S)-2-[[4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-4,4-difluoropyrrolidin-1-yl]-3-oxopropanenitrile 
• 1419387-85-1 C₄₇H₅₆F₄N₄O₁₂ 
• 156046-05-8 (S)-4,4-difluoroproline methyl ester hydrochloride 
• 915230-15-8 (S)-4,4-difluoro-N-tosyl-pyrrolidine-2-carboxylic acid methyl ester 
• 1363384-67-1 tert-butyl (2S)-2-(aminomethyl)-4,4-difluoropyrrolidine-1-carboxylate 
• 869489-04-3 (S)-4,4-difluoropyrrolidine-2-carbonitrile hydrochloride 

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