5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione

Base Information

Chemical Name:5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione
CAS No.:156630-84-1
Molecular Formula:C24H45NO6Si2
Molecular Weight:499.795
Hs Code.:
DSSTox Substance ID:DTXSID20450689
Nikkaji Number:J1.583.419F
Wikidata:Q82270493

5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione

Synonyms:DTXSID20450689;156630-84-1;2,2,5-Trimethyl-5-[(2S)-1-(tert-butyldimethylsilyl)-3beta-[(R)-1-(tert-butyldimethylsiloxy)ethyl]-4-oxoazetidine-2alpha-yl]-1,3-dioxane-4,6-dione;5-{(2S,3S)-1-[tert-Butyl(dimethyl)silyl]-3-[(1R)-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl]-4-oxoazetidin-2-yl}-2,2,5-trimethyl-1,3-dioxane-4,6-dione

Suppliers and Price of 5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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American Custom Chemicals Corporation
5-((2S,3S)-1-(TERT-BUTYLDIMETHYLSILYL)-3-((R)-1-(TERT-BUTYLDIMETHYLSILYLOXY)ETHYL)-4-OXOAZETIDIN-2-YL)-2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE 95.00%
5MG
$ 495.89

Total 0 raw suppliers

Chemical Property of 5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione

Chemical Property:

PSA：82.14000
LogP:5.00920
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:499.27854122
Heavy Atom Count:33
Complexity:817

Purity/Quality:: 5-((2S,3S)-1-(TERT-BUTYLDIMETHYLSILYL)-3-((R)-1-(TERT-BUTYLDIMETHYLSILYLOXY)ETHYL)-4-OXOAZETIDIN-2-YL)-2,2,5-TRIMETHYL-1,3-DIOXANE-4,6-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1C(N(C1=O)[Si](C)(C)C(C)(C)C)C2(C(=O)OC(OC2=O)(C)C)C)O[Si](C)(C)C(C)(C)C
Isomeric SMILES:C[C@H]([C@@H]1[C@H](N(C1=O)[Si](C)(C)C(C)(C)C)C2(C(=O)OC(OC2=O)(C)C)C)O[Si](C)(C)C(C)(C)C

Technology Process of 5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione

There total 3 articles about 5-[(2S,3S)-1-[tert-butyl(dimethyl)silyl]-3-[(1R)-1-[tert-butyl(dimethyl)silyl]oxyethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl-1,3-dioxane-4,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 156630-83-0
5-[(2S,3S)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-oxoazetidin-2-yl]-2,2,5-trimethyl[1,3]dioxane-4,6-dione

: 156630-84-1
5-{(2S,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2,2,5-trimethyl-[1,3]dioxane-4,6-dione

Guidance literature:: With triethylamine; sodium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 3h;
DOI:10.1016/0040-4039(94)85197-2

Reference yield:

: 3709-18-0
2,2,5-trimethyl-1,3-dioxane-4,6-dione

: 156630-84-1
5-{(2S,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2,2,5-trimethyl-[1,3]dioxane-4,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Et₃N / ethyl acetate / 4 h / 65 °C

2: 95 percent / NaI, Et₃N / dimethylformamide / 3 h / 60 °C

With triethylamine; sodium iodide; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(94)85197-2

Reference yield:

: 76899-07-5,78963-47-0,78963-48-1,78963-60-7,80951-41-3,81275-02-7,85647-75-2,85954-95-6,92217-74-8,104527-11-9,76855-69-1
(3R,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-acetoxyazetidin-2-one

: 156630-84-1
5-{(2S,3S)-1-(tert-Butyl-dimethyl-silanyl)-3-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl}-2,2,5-trimethyl-[1,3]dioxane-4,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / Et₃N / ethyl acetate / 4 h / 65 °C

2: 95 percent / NaI, Et₃N / dimethylformamide / 3 h / 60 °C

With triethylamine; sodium iodide; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(94)85197-2