Thiazole-4,5-diyldimethanol

Base Information

Chemical Name:Thiazole-4,5-diyldimethanol
CAS No.:1393686-89-9
Molecular Formula:C5H7NO2S
Molecular Weight:145.18
Hs Code.:2934100090
Mol file:1393686-89-9.mol

Synonyms:Thiazole-4,5-diyldimethanol;[5-(hydroxymethyl)thiazol-4-yl]methanol;4,5-Thiazoledimethanol

Suppliers and Price of Thiazole-4,5-diyldimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4,5-Di(hydroxymethyl)thiazole
1g
$ 323.00

Alichem
Thiazole-4,5-diyldimethanol
1g
$ 477.00

Crysdot
Thiazole-4,5-diyldimethanol 95+%
1g
$ 420.00

Total 5 raw suppliers

Chemical Property of Thiazole-4,5-diyldimethanol

Chemical Property:

Boiling Point:349.5±32.0 °C(Predicted)
PKA:13.24±0.10(Predicted)
PSA：81.59000
Density:1.455±0.06 g/cm3(Predicted)
LogP:0.12770
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4,5-Di(hydroxymethyl)thiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Thiazole-4,5-diyldimethanol

There total 1 articles about Thiazole-4,5-diyldimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 18940-72-2
diethyl thiazole-4,5-dicarboxylate

: 1393686-89-9
[5-(hydroxymethyl)thiazol-4-yl]methanol

Guidance literature:: With lithium borohydride; In tetrahydrofuran; methanol; at 20 ℃; for 1h;
DOI:10.3987/COM-12-12481

Reference yield: 58.0%

: 6325-93-5
p-nitrobenzenesulfonamide

: 1393686-89-9
[5-(hydroxymethyl)thiazol-4-yl]methanol

: 1393686-90-2
5-(4-nitrophenyl)sulfonyl-4,6-dihydropyrrolo[3,4-d]thiazole

Guidance literature:: With cyanomethylenetributyl-phosphorane; In tetrahydrofuran; toluene; at 80 ℃; for 2.5h; Inert atmosphere;
DOI:10.3987/COM-12-12481

Reference yield:

: 1393686-89-9
[5-(hydroxymethyl)thiazol-4-yl]methanol

: C₂₆H₂₆F₄N₄O₅S

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1H-imidazole / N,N-dimethyl-formamide / 60 - 80 °C

2.1: n-butyllithium / tetrahydrofuran / -78 °C / Inert atmosphere

2.2: 1 h / -78 - 0 °C / Inert atmosphere

3.1: hydrogenchloride / methanol / 1 h / 20 °C

4.1: N-ethyl-N,N-diisopropylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / N,N-dimethyl-formamide / Inert atmosphere

With 1H-imidazole; hydrogenchloride; n-butyllithium; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2018.04.062