3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione

Base Information

Chemical Name:3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione
CAS No.:81587-41-9
Molecular Formula:C₁₀H₁₀ClN₅S₂
Molecular Weight:299.808
Hs Code.:
NSC Number:194989
DSSTox Substance ID:DTXSID001002065

Synonyms:BRN 5579402;81587-41-9;3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione;N-6'-Chloro-2'(1H)-thioxo-3'-pyridyl-4-amino-2-methylthio-6-pyrimidinylamine;2(1H)-Pyridinethione, 3-((6-amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-;NSC194989;C10H10ClN5S2;DTXSID001002065;C10-H10-Cl-N5-S2;NSC 194989;NSC-194989;LS-132092;3-{[6-Amino-2-(methylsulfanyl)pyrimidin-4(3H)-ylidene]amino}-6-chloropyridine-2-thiol

Suppliers and Price of 3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione

Chemical Property:

Vapor Pressure:2.1E-09mmHg at 25°C
Boiling Point:480.8°Cat760mmHg
Flash Point:244.6°C
Density:1.57g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:299.0066154
Heavy Atom Count:18
Complexity:398

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC(=CC(=N1)NC2=CC=C(NC2=S)Cl)N

Technology Process of 3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione

There total 4 articles about 3-((6-Amino-2-(methylthio)-4-pyrimidinyl)amino)-6-chloro-2(1H)-pyridinethione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 27467-92-1
3-amino-6-chloropyridine-2<1H>-thione

: 1005-38-5
4-amino-6-chloro-2-methylthiopyrimidine

: 81587-41-9
N-6'-chloro-2'<1H>-thioxo-3'-pyridyl-4-amino-2-methylthio-6-pyrimidinylamine

Guidance literature:: With sulfuric acid; sodium sulfite; In water; for 5h; Heating;
DOI:10.1248/cpb.30.302

Reference yield:

: 5350-93-6
6-Chloro-pyridin-3-ylamine

: 81587-41-9
N-6'-chloro-2'<1H>-thioxo-3'-pyridyl-4-amino-2-methylthio-6-pyrimidinylamine

Guidance literature:: Multi-step reaction with 3 steps

1: Br₂ / acetic acid / 0 - 5 °C

2: HO^- / Heating

3: 60 percent / cc. sulfuric acid, sodium sulfite / H₂O / 5 h / Heating

With sulfuric acid; hydroxide; bromine; sodium sulfite; In water; acetic acid;
DOI:10.1248/cpb.30.302

Reference yield:

: 4548-45-2
2-chloro-5-nitropyridine

: 81587-41-9
N-6'-chloro-2'<1H>-thioxo-3'-pyridyl-4-amino-2-methylthio-6-pyrimidinylamine

Guidance literature:: Multi-step reaction with 4 steps

1: iron, calcium chloride / aq. ethanol / 2 h / Heating

2: Br₂ / acetic acid / 0 - 5 °C

3: HO^- / Heating

4: 60 percent / cc. sulfuric acid, sodium sulfite / H₂O / 5 h / Heating

With sulfuric acid; hydroxide; bromine; iron; calcium chloride; sodium sulfite; In ethanol; water; acetic acid;
DOI:10.1248/cpb.30.302