1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)-

Base Information

Chemical Name:1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)-
CAS No.:949925-07-9
Molecular Formula:C12H14N2O2
Molecular Weight:218.255
Hs Code.:
UNII:X4X99EKB3S
Nikkaji Number:J3.159.450B

Synonyms:2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide;MRZ-9546;MRZ-9547

Suppliers and Price of 1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of 1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)-

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:218.105527694
Heavy Atom Count:16
Complexity:285

Purity/Quality:: 99% ,98%,Electron Grade , ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CN(C1=O)CC(=O)N)C2=CC=CC=C2
Isomeric SMILES:C1[C@@H](CN(C1=O)CC(=O)N)C2=CC=CC=C2

Technology Process of 1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)-

There total 9 articles about 1-Pyrrolidineacetamide, 2-oxo-4-phenyl-, (4R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 949925-06-8
ethyl [(4R)-2-oxo-4-phenylpyrrolidin-1-yl]acetate

: 949925-07-9
2-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]acetamide

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 5h;
DOI:10.1134/S1070428013050047

Reference yield:

: 1402044-28-3
n-butyl 3(R)-4-amino-3-phenylbutyrate hydrochloride

: 949925-07-9
2-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium phosphate monohydrate / N,N-dimethyl-formamide / 48 h / 20 °C / Molecular sieve

2: potassium phosphate monohydrate; tetrabutylammomium bromide / toluene / 2 h / Reflux

With potassium phosphate monohydrate; tetrabutylammomium bromide; In N,N-dimethyl-formamide; toluene;
DOI:10.1007/s10593-012-1050-y

Reference yield:

: 1402044-29-4
n-butyl (3R)-4-carbamoylmethylamino-3-phenylbutyrate

: 949925-07-9
2-[(4R)-2-oxo-4-phenylpyrrolidin-1-yl]acetamide

Guidance literature:: With potassium phosphate monohydrate; tetrabutylammomium bromide; In toluene; for 2h; Reflux;
DOI:10.1007/s10593-012-1050-y