2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE

Base Information

Chemical Name:2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE
CAS No.:1161004-77-8
Molecular Formula:C12H11F3N2O2
Molecular Weight:272.227
Hs Code.:2933990090
Mol file:1161004-77-8.mol

Synonyms:2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE

Suppliers and Price of 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE

Chemical Property:

PSA：41.90000
LogP:2.24090

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE

There total 1 articles about 2-(4-METHOXYPHENYL)-6-(TRIFLUOROMETHYL)-4,5-DIHYDROPYRIDAZIN-3(2H)-ONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 22581-31-3
methyl 5,5,5-trifluoro-4-oxopentanoate

: 3471-32-7
4-Methoxyphenylhydrazine

: 1161004-77-8
2-(4-methoxyphenyl)-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one

: C₁₃H₁₅F₃N₂O₃

Guidance literature:: With toluene-4-sulfonic acid; In toluene; for 24h; Inert atmosphere; Reflux;
DOI:10.1016/j.tet.2009.03.029

Reference yield: 93.0%

: 1161004-77-8
2-(4-methoxyphenyl)-6-(trifluoromethyl)-4,5-dihydropyridazin-3(2H)-one

: C₁₂H₁₃F₃N₂O₂

Guidance literature:: With (S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine); palladium(II) trifluoroacetate; hydrogen; trifluoroacetic acid; at 80 ℃; for 48h; under 51716.2 Torr;
DOI:10.1021/acscatal.5b01641