3471-32-7

Basic information

• Product Name: (4-methoxyphenyl)hydrazine
• Synonyms: 1-(4-Methoxyphenyl)hydrazine;4-Methoxy-1-hydrazinobenzene;p-Methoxyphenylhydrazine;Einecs 222-439-9;Hydrazine, (4-methoxyphenyl)-;p-Anisylhydrazine
• CAS NO: 3471-32-7
• Molecular Formula: C₇H₁₀N₂O
• Molecular Weight: 138.17
• EINECS: 222-439-9
• Mol File: 3471-32-7.mol
• Article Data: 30

Chemical Properties

• Melting Point: 65 °C
• Boiling Point: 277.8 °C at 760 mmHg
• Flash Point: 121.8 °C
• Appearance: /
• Density: 1.15 g/cm³
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 5.50±0.20(Predicted)
• CAS DataBase Reference: (4-methoxyphenyl)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxyphenyl)hydrazine(3471-32-7)
• EPA Substance Registry System: (4-methoxyphenyl)hydrazine(3471-32-7)

Safety Data

• Hazardous Substances Data: 3471-32-7(Hazardous Substances Data)

Usage

Uses

(4-Methoxyphenyl)hydrazine is a useful reagent for the preparation of pyrazolopyridazine derivatives as anticancer agents.

InChI:InChI=1/C7H10N2O/c1-10-7-4-2-6(9-8)3-5-7/h2-5,9H,8H2,1H3

Upstream product

• 23197-23-1 4-hydroxyphenylhydrazine 
• 74-88-4 methyl iodide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 696-62-8 para-iodoanisole 
• 623-12-1 4-chloromethoxybenzene 
• 95854-01-6 7-nicotinoylheptanoic acid 
• 219753-93-2 di-tert-butyl 1-(4-methoxyphenyl)hydrazine-1,2-dicarboxylate 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 104-94-9 4-methoxy-aniline 
• 4346-59-2 para-methoxyphenyldiazonium chloride 
• 17333-79-8 p-methoxybenzenediazonium 

Downstream Products

• 62833-10-7 ethyl 2-(4-methoxyphenyl)hydrazinecarboxylate 
• 5705-10-2 N-benzyl-N-(4-methoxy-phenyl)-hydrazine; hydrochloride 
• 17473-78-8 N’-(4-methoxyphenyl)acetohydrazide 
• 3449-49-8 6-methoxy-2,3,4,9-tetrahydro-1H-carbazol-1-one 
• 35699-51-5 2-(4-Methoxyphenylazo)-isobutyronitril 
• 60078-07-1 N'-(4-Methoxy-phenyl)-hydrazinecarbodithioic acid 
• 65149-36-2 2,2,2-trifluoro-N'-(4-methoxyphenyl)acetohydrazide 
• 35223-00-8 4-methoxy-thiobenzoic acid N'-(4-methoxy-phenyl)-hydrazide 
• 7382-39-0 1-(p-methoxyphenyl)-3-thiosemicarbazide 
• 35222-96-9 N'-(p-methoxyphenyl)benzothiohydrazide 
• 134504-11-3 (3,4,6,7,8,9-Hexahydro-2H-quinolizin-1-yl)-(4-methoxy-phenyl)-diazene 
• 13637-14-4 9-methoxy-1,2,3,4,6,7,12,12b-octahydro-indolo[2,3-a]quinolizine 
• 95526-13-9 N-(4-Methoxy-phenyl)-N'-[1-phenyl-1-pyridin-2-yl-meth-(Z)-ylidene]-hydrazine 
• 103973-42-8 deoxybenzoin p-methoxyphenylhydrazone 

Relevant articles and documents

Synthesis, structure and supramolecular properties of 1,7′-bis[4-(3-methyl-2,3-dihydro-pyrazol-1-yl)phenol]-1,4,7-trioxaheptane

A new pyrazole derivative, 1,7′-bis[4-(3-methyl-2,3-dihydro-pyrazol-1-yl)phenol]-1,4,7-trioxaheptane with m.f. C24H24N4O5 has been synthesized and the crystal structure was determined by single crystal X-ray diffraction. Interestingly, the title compound are linked by intermolecular O2-H22?N2 hydrogen bonds into a 36 atoms' macro-ring which is further held together into one dimensional beaded chain via C-H?O hydrogen bonding between another phenol oxygen atom and one methylene carbon atom.

Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine

In this work, we developed a ligand- and base-free visible-light-mediated protocol for the photoredox syntheses of arylphosphonates and, for the first time, alkyl phosphonates. Zinc phthalocyanine-photocatalyzed Csp2-P and Csp3-P bond formations were efficiently achieved by reacting aryl/alkylhydrazines with trialkylphosphites in the presence of air serving as an abundant oxidant. The reaction conditions tolerated a wide variety of functional groups.

One-Pot Synthesis of Indoles and Pyrazoles via Pd-Catalyzed Couplings/Cyclizations Enabled by Aqueous Micellar Catalysis

An effective one-pot synthesis of either indoles or pyrazoles can be achieved via Pd-catalyzed aminations followed by subsequent cyclizations facilitated by aqueous micellar catalysis. This new technology includes efficient couplings with low loadings of palladium, a more stable source of the required hydrazine moiety, greater atom economy for the initial coupling, and reduced reaction temperatures, all leading to environmentally responsible processes.