Oxycodone-N-methyl-d3 Hydrochloride

Base Information

• Chemical Name: Oxycodone-N-methyl-d3 Hydrochloride
• CAS No.: 145225-02-1
• Molecular Formula: C₁₈H₂₁NO₄
• Molecular Weight: 318.345
• Mol file: 145225-02-1.mol

Synonyms:(4S,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-(trideuteriomethyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one,hydrochloride;

Chemical Property of Oxycodone-N-methyl-d3 Hydrochloride

Chemical Property:

• Melting Point: 181-1840C
• PSA: 59.00000
• LogP: 1.78810
• Storage Temp.: Controlled Substance, -20°C Freezer

Purity/Quality:

97% ^*data from raw suppliers

Oxycodone-d3 (CRM) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Labelled Oxycodone. Controlled substance (opiate). Analgesic (narcotic).

Technology Process of Oxycodone-N-methyl-d3 Hydrochloride

There total 1 articles about Oxycodone-N-methyl-d3 Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

iodomethane-d3 (865-50-9) + noroxycodone (57664-96-7) → oxycodone-D3 (145225-02-1)

Guidance literature:

With potassium carbonate; In methanol; acetone; at 20 ℃; for 24h;

DOI:10.1021/acs.orglett.0c02424

upstream raw materials:

iodomethane-d3

noroxycodone

Refernces