MOXIFLOXACIN

Base Information

Chemical Name:MOXIFLOXACIN
CAS No.:158060-78-7
Molecular Formula:C₂₁H₂₄FN₃O₄
Molecular Weight:401.438
Hs Code.:
Mol file:158060-78-7.mol

Synonyms:3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, trans- (9CI)

Suppliers and Price of MOXIFLOXACIN

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of MOXIFLOXACIN

Chemical Property:

Boiling Point:636.4±55.0 °C(Predicted)
PKA:6.43±0.50(Predicted)
Density:1.408±0.06 g/cm3(Predicted)

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of MOXIFLOXACIN

There total 19 articles about MOXIFLOXACIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 151213-40-0,158060-81-2,169533-56-6
(1S,6S)-2,8-diazabicyclo[4.3.0]nonane

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With [BCl₂(4-picoline)][AlCl₄]; triethylamine; In methanol; at 85 ℃; for 6h; Reagent/catalyst; Solvent; Temperature; Catalytic behavior;

Reference yield: 96.0%

: 151213-42-2,158060-81-2,169533-56-6
[R,R]-2,8-diazabicyclo[4.3.0]nonane

: 112811-72-0
1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid

: 1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: With nano iron oxide on ZrO₂ coated sulfonic acid; In water; for 0.416667h; Reflux;
DOI:10.2174/1570178615666171226162735

Reference yield: 90.0%

: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.

: 151096-09-2,1346747-14-5,158060-78-7,195154-07-5,268545-13-7,354812-41-2
moxifloxacin

Guidance literature:: (4aS-cis)-1-cyclopropyl-7-(2,8 diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydro-3-quinoline carboxylic aid-O₃,O₄-bis(propyloxy-O)borate.; With hydrogenchloride; In methanol; water; at 10 - 15 ℃; for 2h; pH=1.0 - 2.0;

With ammonia; In water; at 25 - 75 ℃; for 1.25h; pH=7.5 - 8; Product distribution / selectivity;