4-Methylenepiperidine hydrobroMide

Base Information

• Chemical Name: 4-Methylenepiperidine hydrobroMide
• CAS No.: 3522-98-3
• Molecular Formula: BrH*C₆H₁₁N
• Molecular Weight: 178.072
• Mol file: 3522-98-3.mol

Synonyms:4-Methylenepiperidine hydrobroMide

Chemical Property of 4-Methylenepiperidine hydrobroMide

Chemical Property:

• PSA: 12.03000
• LogP: 2.21290

Purity/Quality:

99%, ^*data from raw suppliers

4-Methylenepiperidinehydrobromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methylenepiperidine hydrobroMide

There total 6 articles about 4-Methylenepiperidine hydrobroMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

4-methylene piperidine (148133-82-8) → 4-methylenepiperidine hydrobromide (3522-98-3)

Guidance literature:

With hydrogen bromide;

Reference yield: 90.0%

4-methylene piperidine (148133-82-8) → 4-methylenepiperidine hydrobromide (3522-98-3)

Guidance literature:

With hydrogen bromide; In methanol; water; for 1h; Cooling with ice;

Reference yield: 79.6%

tert-butyl 4-methylidenepiperidine-1-carboxylate (159635-49-1) → 4-methylenepiperidine hydrobromide (3522-98-3)

Guidance literature:

With hydrogen bromide; In methanol;

upstream raw materials:

4-methylene piperidine

tert-butyl 4-methylidenepiperidine-1-carboxylate

1,5-dichloropentan-3-one

α,α'-dibromopentan-3-one

Refernces

• 1、 -. "Method for preparation of Efinaconazole". Paragraph 0071; 0072; 0073. . Retrieved 2017/08/28.