Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate

Base Information

Chemical Name:Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate
CAS No.:92378-74-0
Molecular Formula:C13H10N4O5
Molecular Weight:302.2423
Hs Code.:
DSSTox Substance ID:DTXSID10704562
Nikkaji Number:J584.004J
Wikidata:Q82637017
Mol file:92378-74-0.mol

Synonyms:92378-74-0;DTXSID10704562;FT-0763412;Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate;3-[(4-Nitrobenzoyl)amino]-2-pyrazinecarboxylic acid methyl ester

Suppliers and Price of Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate

Chemical Property:

PSA：130.23000
LogP:1.36880
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:302.06511943
Heavy Atom Count:22
Complexity:431

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=NC=CN=C1NC(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate

There total 4 articles about Methyl 3-(4-nitrobenzamido)pyrazine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 155513-76-1
3-[Bis-(4-nitro-benzoyl)-amino]-pyrazine-2-carboxylic acid methyl ester

: 92378-74-0
3-(4-nitro-benzoylamino)-pyrazine-2-carboxylic acid methyl ester

Guidance literature:: With hydrazine hydrate; In 1,4-dioxane; isopropyl alcohol; for 0.5h; Heating;
DOI:10.1055/s-1994-25487

Reference yield:

: 16298-03-6
Methyl 3-amino-2-pyrazinecarboxylate

: 92378-74-0
3-(4-nitro-benzoylamino)-pyrazine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / pyridine / 2 h / 50 °C

2: 65 percent / 98percent hydrazine hydrate / dioxane; propan-2-ol / 0.5 h / Heating

With pyridine; hydrazine hydrate; In 1,4-dioxane; isopropyl alcohol;
DOI:10.1055/s-1994-25487

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 92378-74-0
3-(4-nitro-benzoylamino)-pyrazine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / pyridine / 2 h / 50 °C

2: 65 percent / 98percent hydrazine hydrate / dioxane; propan-2-ol / 0.5 h / Heating

With pyridine; hydrazine hydrate; In 1,4-dioxane; isopropyl alcohol;
DOI:10.1055/s-1994-25487