2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Base Information

Chemical Name:2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER
CAS No.:74476-62-3
Molecular Formula:C12H9ClN2O4S
Molecular Weight:312.733
Hs Code.:
Mol file:74476-62-3.mol

Synonyms:2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Suppliers and Price of 2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

Chemical Property:

PSA：113.25000
LogP:4.07160

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER

There total 4 articles about 2-CHLORO-4-(4-NITROPHENYL)-5-THIAZOLECARBOXYLIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glacial HOAc: glacial HOAc

: 68301-50-8
ethyl 2-amino-4-(4-nitrophenyl)thiazole-5-carboxylate

: 74476-62-3
ethyl 2-chloro-4-p-nitrophenyl-5-thiazolecarboxylate

Guidance literature:: With sodium nitrite; copper(l) chloride; In hydrogenchloride; water;

Reference yield:

: 838-57-3
ethyl 4-nitrobenzoylacetate

: 74476-62-3
ethyl 2-chloro-4-p-nitrophenyl-5-thiazolecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: SO₂Cl₂

2: 81 percent / ethanol / 16 h / Heating

3: 1.) aq. HCl, CuSO₄, NaNO₂, 2.) conc. HCl, CuCl / 1.) CHCl₃;

With hydrogenchloride; sulfuryl dichloride; copper(II) sulfate; copper(l) chloride; sodium nitrite; In ethanol;

Reference yield:

: 74476-72-5
ethyl 2-chloro-3-(4-nitrophenyl)-3-oxopropanoate

: 74476-62-3
ethyl 2-chloro-4-p-nitrophenyl-5-thiazolecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / ethanol / 16 h / Heating

2: 1.) aq. HCl, CuSO₄, NaNO₂, 2.) conc. HCl, CuCl / 1.) CHCl₃;

With hydrogenchloride; copper(II) sulfate; copper(l) chloride; sodium nitrite; In ethanol;