3-amino-N-cyclopropylbenzamide

Base Information

Chemical Name:3-amino-N-cyclopropylbenzamide
CAS No.:871673-24-4
Molecular Formula:C10H12N2O
Molecular Weight:176.218
Hs Code.:2924299090
European Community (EC) Number:846-715-9
DSSTox Substance ID:DTXSID50427703
Wikidata:Q82240369
Mol file:871673-24-4.mol

Synonyms:3-amino-N-cyclopropylbenzamide;871673-24-4;SCHEMBL3646204;DTXSID50427703;HMS1758F15;WJB67324;BBL030739;MFCD07355824;STK899002;AKOS000264179;VS-10007;BB 0218409;CS-0456750;EN300-15035;F78851;A862757;Z111875424

Suppliers and Price of 3-amino-N-cyclopropylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Amino-N-cyclopropylbenzamide
500mg
$ 140.00

TRC
3-Amino-N-cyclopropylbenzamide
100mg
$ 55.00

Crysdot
3-Amino-N-cyclopropylbenzamide 95+%
10g
$ 561.00

Crysdot
3-Amino-N-cyclopropylbenzamide 95+%
5g
$ 356.00

Chemenu
3-Amino-N-cyclopropylbenzamide 95%
10g
$ 525.00

Chemenu
3-Amino-N-cyclopropylbenzamide 95%
5g
$ 333.00

Apolloscientific
3-Amino-N-cyclopropylbenzamide 96%
1g
$ 232.00

Apolloscientific
3-Amino-N-cyclopropylbenzamide 96%
5g
$ 734.00

AK Scientific
3-Amino-N-cyclopropylbenzamide
5g
$ 557.00

AK Scientific
3-Amino-N-cyclopropylbenzamide
1g
$ 211.00

Total 9 raw suppliers

Chemical Property of 3-amino-N-cyclopropylbenzamide

Chemical Property:

Boiling Point:389.5±25.0 °C(Predicted)
PKA:14.89±0.20(Predicted)
PSA：58.61000
Density:1.20±0.1 g/cm3(Predicted)
LogP:2.31700
Storage Temp.:2-8°C
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:201

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-N-cyclopropylbenzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC1NC(=O)C2=CC(=CC=C2)N

Technology Process of 3-amino-N-cyclopropylbenzamide

There total 3 articles about 3-amino-N-cyclopropylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 392709-17-0
N-cyclopropyl-3-nitrobenzamide

: 871673-24-4
3-amino-N-cyclopropylbenzamide

Guidance literature:: With tin(II) chloride hydrate; In ethanol; at 100 ℃; for 2h; Inert atmosphere; Schlenk technique;
DOI:10.1021/jm5009242

Reference yield: 56.0%

: 99-05-8,159139-79-4
meta-aminobenzoic acid

: 765-30-0
Cyclopropylamine

: 871673-24-4
3-amino-N-cyclopropylbenzamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.ejmech.2020.113033

Reference yield:

: 121-92-6
3-nitrobenzoic acid

: 871673-24-4
3-amino-N-cyclopropylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 15 h / 25 °C / Inert atmosphere; Schlenk technique

2: tin(II) chloride hydrate / ethanol / 2 h / 100 °C / Inert atmosphere; Schlenk technique

With tin(II) chloride hydrate; triethylamine; In ethanol; dichloromethane;
DOI:10.1021/jm5009242