ISOAPOPTOLIDIN

Base Information

• Chemical Name: ISOAPOPTOLIDIN
• CAS No.: 476647-30-0
• Molecular Formula: C₅₈H₉₆O₂₁
• Molecular Weight: 1129.39
• Mol file: 476647-30-0.mol

Synonyms:ISOAPOPTOLIDIN

Chemical Property of ISOAPOPTOLIDIN

Chemical Property:

• PSA: 289.67000
• LogP: 3.58730

Purity/Quality:

98%Min ^*data from raw suppliers

Isoapoptolidin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isopoptolidin, originally isolated from a Nocardiopsis sp., is a ring-expanded isomer of apoptolidin. In water, apoptolidin and isoapoptolidin equilibrate in a ratio of ~1.5:1 within hours. In a rapid F0F1-ATPase assay, isoapoptolidin was approximately half as potent as apoptolidin (IC50 17 μM vs. 0.7 μM ). Isoapoptolidin, originally isolated from a Nocardiopsis sp., is a ring-expanded isomer of apoptolidin. In water, apoptolidin and isoapoptolidin equilibrate in a ratio of ~1.5:1 within hours. In a rapid F0F1-ATPase assay, isoapoptolidin was approximately half as potent as apoptolidin (IC50 17 μM vs. 0.7 μM ). Isoapoptolidin is a ring expanded isomer of apoptolidin.

Technology Process of ISOAPOPTOLIDIN

There total 1 articles about ISOAPOPTOLIDIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

apoptolidin (194874-06-1) → isoapoptolidin A (476647-30-0)

Guidance literature:

In various solvent(s); at 37 ℃; Kinetics;

DOI:10.1021/ol0266222

Reference yield:

isoapoptolidin A (476647-30-0) → apoptolidin (194874-06-1)

Guidance literature:

In various solvent(s); at 37 ℃; Kinetics;

DOI:10.1021/ol0266222

upstream raw materials:

apoptolidin

Downstream raw materials:

apoptolidin