4-Bromo-2-(trifluoromethyl)-1H-indole

Base Information

Chemical Name:4-Bromo-2-(trifluoromethyl)-1H-indole
CAS No.:955978-75-3
Molecular Formula:C9H5BrF3N
Molecular Weight:264.045
Hs Code.:2933998090
DSSTox Substance ID:DTXSID60695037
Wikidata:Q82624024
Mol file:955978-75-3.mol

Synonyms:4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE;955978-75-3;4-Bromo-2-(trifluoromethyl)indole;MFCD17215879;SCHEMBL993353;DTXSID60695037;4-Bromo-2-trifluoromethyl-1H-indole;AKOS022675501;AS-35567;SY031151;CS-0171070;EN300-135734;A859001

Suppliers and Price of 4-Bromo-2-(trifluoromethyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Bromo-2-(trifluoromethyl)-1H-indole
1 g
$ 416.00

SynQuest Laboratories
4-Bromo-2-(trifluoromethyl)-1H-indole
250 mg
$ 136.00

SynQuest Laboratories
4-Bromo-2-(trifluoromethyl)-1H-indole
5 g
$ 1112.00

Crysdot
4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE 95+%
5g
$ 1205.00

Crysdot
4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE 95+%
250mg
$ 230.00

Crysdot
4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE 95+%
1g
$ 401.00

Chemenu
4-bromo-2-(trifluoromethyl)-1H-indole 95%
1g
$ 393.00

Chemenu
4-bromo-2-(trifluoromethyl)-1H-indole 95%
5g
$ 1374.00

AstaTech
4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE 97%
5 / G
$ 1214.00

AstaTech
4-BROMO-2-(TRIFLUOROMETHYL)-1H-INDOLE 97%
1 / G
$ 405.00

Total 6 raw suppliers

Chemical Property of 4-Bromo-2-(trifluoromethyl)-1H-indole

Chemical Property:

PSA：15.79000
LogP:3.94920
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:262.95575
Heavy Atom Count:14
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

4-Bromo-2-(trifluoromethyl)-1H-indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C(N2)C(F)(F)F)C(=C1)Br

Technology Process of 4-Bromo-2-(trifluoromethyl)-1H-indole

There total 5 articles about 4-Bromo-2-(trifluoromethyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 955978-77-5
N-[3-bromo-2-(bromomethyl)phenyl]-2,2,2-trifluoroacetamide

: 955978-75-3
4-bromo-2-(trifluoromethyl)-1H-indole

Guidance literature:: N-[3-bromo-2-(bromomethyl)phenyl]-2,2,2-trifluoroacetamide; With triphenylphosphine; In toluene; at 60 ℃; for 2h;

In N,N-dimethyl-formamide; Reflux;

Reference yield:

: C₉H₅BrF₃NO₃

: 955978-75-3
4-bromo-2-(trifluoromethyl)-1H-indole

Guidance literature:: With acetic acid; zinc; In ethanol; at -50 - 20 ℃; regioselective reaction;
DOI:10.1016/j.tetlet.2021.153515

Reference yield:

: 955978-76-4
N-(3-bromo-2-methylphenyl)-2,2,2-trifluoroacetamide

: 955978-75-3
4-bromo-2-(trifluoromethyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: bromine; dibenzoyl peroxide / tetrachloromethane / 16 h / Heating / reflux; UV-irradiation

2.1: triphenylphosphine / toluene / 2 h / 60 °C

2.2: 16 h / Heating / reflux

With bromine; triphenylphosphine; dibenzoyl peroxide; In tetrachloromethane; toluene;