Ticabesone

Base Information

Chemical Name:Ticabesone
CAS No.:74131-77-4
Molecular Formula:C₂₂H₂₈F₂O₄S
Molecular Weight:426.525
Hs Code.:
Mol file:74131-77-4.mol

Synonyms:Ticabesone;6α,9-Difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-methyl ester;Ticabesone [inn]

Suppliers and Price of Ticabesone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TICABESONE 95.00%
5MG
$ 498.94

Total 3 raw suppliers

Chemical Property of Ticabesone

Chemical Property:

Boiling Point:554.7±50.0 °C(Predicted)
PKA:11.98±0.70(Predicted)
PSA：99.90000
Density:1.34±0.1 g/cm3(Predicted)
LogP:3.17190

Purity/Quality:

99% ^*data from raw suppliers

TICABESONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ticabesone

There total 1 articles about Ticabesone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 28416-82-2
6α,9α-difluoro-11β,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylic acid

: 5188-07-8
sodium thiomethoxide

: 101916-42-1
6α,9α-difluoro-16α,17-dimethyl-11β-hydroxy-18-norandrosta-1,4,13(17)-trien-3-one

: 101916-43-2
6α,9α-difluoro-11β,13α-dihydroxy-16α,17β-dimethyl-3-oxo-18-norandrosta-1,4-diene-17α-carboxylic acid 13-lactone

: 74131-77-4
6α,9α-difluoro-11β,17α-dihydroxy-17β-[(methylthio)carbonyl]-16α-methylandrosta-1,4-dien-3-one

Guidance literature:: With TEA; 1-methyl-2-fluoropyridinium p-toluenesulfonate; Yield given. Multistep reaction. Yields of byproduct given; 1.) CH₂Cl₂, -15 deg C, 20 min, 2.) CH₂Cl₂, DMF, -15 deg C, 16 h;
DOI:10.1021/jo00362a028