5-aMino-6-broMo-1-naphthonitrile

Base Information

• Chemical Name: 5-aMino-6-broMo-1-naphthonitrile
• CAS No.: 1240642-73-2
• Molecular Formula: C11H7BrN2
• Molecular Weight: 247.09068
• Hs Code.: 2922390090
• Mol file: 1240642-73-2.mol

Synonyms:5-aMino-6-broMo-1-naphthonitrile;5-aMino-6-broMo-naphthalene-1-carbonitrile;5-amino-6-bromo-1-Naphthalenecarbonitrile

Chemical Property of 5-aMino-6-broMo-1-naphthonitrile

Chemical Property:

• PSA: 49.81000
• LogP: 3.63738

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-6-bromo-1-naphthonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-aMino-6-broMo-1-naphthonitrile

There total 1 articles about 5-aMino-6-broMo-1-naphthonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

5-Aminonaphthalene-1-carbonitrile (72016-73-0) → C11H7BrN2 (1240642-73-2)

Guidance literature:

With N-Bromosuccinimide; silica gel; In acetonitrile; at 20 ℃; for 16h; regioselective reaction;

Reference yield: 99.0%

3-(N,N-dimethylamino)phenylboronic acid (178752-79-9) + C11H7BrN2 (1240642-73-2) → 5-amino-6-(3-(dimethylamino)phenyl)-1-naphthonitrile (1240642-74-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; benzene; for 24h; Reflux; Inert atmosphere;

DOI:10.1021/ja1040013

upstream raw materials:

5-Aminonaphthalene-1-carbonitrile

Downstream raw materials:

5-amino-6-(3-(dimethylamino)phenyl)-1-naphthonitrile