FMoc-(S)-3-AMino-5-hexynoic acid

Base Information

Chemical Name:FMoc-(S)-3-AMino-5-hexynoic acid
CAS No.:1217669-02-7
Molecular Formula:C21H19NO4
Molecular Weight:349.37986
Hs Code.:
Mol file:1217669-02-7.mol

Synonyms:(S)-3-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}hex-5-ynoic acid;Fmoc-L-β3-Pra-OH;

Suppliers and Price of FMoc-(S)-3-AMino-5-hexynoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Fmoc-(S)-3-amino-5-hexynoic acid
1g
$ 814.00

Matrix Scientific
Fmoc-(S)-3-amino-5-hexynoic acid
250mg
$ 300.00

Crysdot
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid 95+%
5g
$ 2376.00

Crysdot
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid 95+%
1g
$ 589.00

Chemenu
(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid 95%
500mg
$ 147.00

Chemenu
(S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid 95%
250mg
$ 92.00

Alichem
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid
5g
$ 2514.75

Alichem
(S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hex-5-ynoicacid
1g
$ 630.70

Total 5 raw suppliers

Chemical Property of FMoc-(S)-3-AMino-5-hexynoic acid

Chemical Property:

PSA：75.63000
LogP:3.78260

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-(S)-3-amino-5-hexynoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of FMoc-(S)-3-AMino-5-hexynoic acid

There total 4 articles about FMoc-(S)-3-AMino-5-hexynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 1417532-33-2
(S)-(9H-fluoren-9-yl)methyl (1-diazo-2-oxohex-5-yn-3-yl)carbamate

: 1217669-02-7,270596-48-0
(S)-3-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}hex-5-ynoic acid

Guidance literature:: With silver trifluoroacetate; In tetrahydrofuran; water; at 20 ℃; for 8h; Inert atmosphere; Darkness; Sonication;
DOI:10.1055/s-0032-1317445 DOI:10.1055/s-0032-1317445

Reference yield:

: 23235-01-0
(2S)-2-amino-4-pentynoic acid

: 1217669-02-7,270596-48-0
(S)-3-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}hex-5-ynoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / water; 1,4-dioxane / 0.5 h / 0 °C / Inert atmosphere

2.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / -20 °C / Inert atmosphere

2.2: 1.5 h / -20 - 0 °C / Inert atmosphere

3.1: silver trifluoroacetate / water; tetrahydrofuran / 8 h / 20 °C / Inert atmosphere; Darkness; Sonication

With 4-methyl-morpholine; silver trifluoroacetate; potassium carbonate; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; water; 3.1: |Arndt-Eistert Homologation;
DOI:10.1055/s-0032-1317445 DOI:10.1055/s-0032-1317445

Reference yield:

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 1217669-02-7,270596-48-0
(S)-3-{[((9H-fluoren-9-yl)methoxy)carbonyl]amino}hex-5-ynoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate / water; 1,4-dioxane / 0.5 h / 0 °C / Inert atmosphere

2.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / -20 °C / Inert atmosphere

2.2: 1.5 h / -20 - 0 °C / Inert atmosphere

3.1: silver trifluoroacetate / water; tetrahydrofuran / 8 h / 20 °C / Inert atmosphere; Darkness; Sonication

With 4-methyl-morpholine; silver trifluoroacetate; potassium carbonate; isobutyl chloroformate; In tetrahydrofuran; 1,4-dioxane; water; 3.1: |Arndt-Eistert Homologation;
DOI:10.1055/s-0032-1317445 DOI:10.1055/s-0032-1317445