(±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol

Base Information

Chemical Name:(±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol
CAS No.:1253909-21-5
Molecular Formula:C19H18N2O5
Molecular Weight:354.362
Hs Code.:
Mol file:1253909-21-5.mol

Synonyms:(±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol

Suppliers and Price of (±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1',3',3'-Trimethyl-6-nitrospiro[chromene-2,2'-indoline]-5',8-diol 97%
1g
$ 474.00

ACHEMBLOCK
1',3',3'-trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]-5',8-diol 98%
1G
$ 950.00

ACHEMBLOCK
1',3',3'-trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]-5',8-diol 98%
5MG
$ 35.00

ACHEMBLOCK
1',3',3'-trimethyl-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]-5',8-diol 98%
100MG
$ 295.00

aablocks
1'',3'',3''-Trimethyl-6-nitrospiro[chromene-2,2''-indoline]-5'',8-diol 98%
25mg
$ 143.00

aablocks
1'',3'',3''-Trimethyl-6-nitrospiro[chromene-2,2''-indoline]-5'',8-diol 98%
5mg
$ 59.00

Total 19 raw suppliers

Chemical Property of (±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol

Chemical Property:

Boiling Point:587.9±50.0 °C(Predicted)
PKA:7.53±0.40(Predicted)
PSA：98.75000
Density:1.48±0.1 g/cm3(Predicted)
LogP:4.12370

Purity/Quality:

97% ^*data from raw suppliers

1',3',3'-Trimethyl-6-nitrospiro[chromene-2,2'-indoline]-5',8-diol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol

There total 9 articles about (±)-1',3',3'-triMethyl-6-nitrospiro[chroMene-2,2'-indoline]-5',8-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 5-hydroxy-1,2,3,3-tetramethyl-3H-indol-1-ium iodide

: 52924-54-6
2,3-dihydroxy-5-nitro-benzaldehyde

: 1253909-21-5
(±)-1',3',3'-trimethyl-6-nitrospiro[chromene-2,2'-indoline]-5',8-diol

Guidance literature:: With piperidine; In ethanol; for 2h; Inert atmosphere; Reflux;
DOI:10.1021/ja106332g

Reference yield:

: 148-53-8
3-methoxy-2-hydroxybenzaldehyde

: 1253909-21-5
(±)-1',3',3'-trimethyl-6-nitrospiro[chromene-2,2'-indoline]-5',8-diol

Guidance literature:: Multi-step reaction with 3 steps

1: nitric acid; acetic acid

2: hydrogen bromide

3: piperidine / ethanol

With piperidine; hydrogen bromide; nitric acid; acetic acid; In ethanol;
DOI:10.1002/anie.202101881

Reference yield:

: 17028-61-4
5-nitro-o-vanilline

: 1253909-21-5
(±)-1',3',3'-trimethyl-6-nitrospiro[chromene-2,2'-indoline]-5',8-diol

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen bromide

2: piperidine / ethanol

With piperidine; hydrogen bromide; In ethanol;
DOI:10.1002/anie.202101881