6alpha-Hydroxyandrostenedione

Base Information

Chemical Name:6alpha-Hydroxyandrostenedione
CAS No.:24704-84-5
Molecular Formula:C19H26O3
Molecular Weight:302.414
Hs Code.:
UNII:1TQ5N1N404
ChEMBL ID:CHEMBL4520027
DSSTox Substance ID:DTXSID90550721
Nikkaji Number:J672.707G
Pharos Ligand ID:17A7NZ29TCGF
Wikidata:Q27252873
Mol file:24704-84-5.mol

Synonyms:24704-84-5;6alpha-hydroxyandrostenedione;6alpha-OH-Adion;UNII-1TQ5N1N404;Androst-4-ene-3,17-dione, 6-hydroxy-, (6alpha)-;J672.707G;1TQ5N1N404;6-OH-Androstenedione, (6alpha)-;(6alpha)-6-Hydroxyandrost-4-ene-3,17-dione;Androst-4-en-6alpha-ol-3,17-dione;6alpha-Hydroxy-4-androstene-3,17-dione;CHEMBL4520027;ANDROST-4-ENE-3,17-DIONE, 6-HYDROXY-, (6.ALPHA.)-;(6S,8R,9S,10R,13S,14S)-6-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione;4-Androsten-6beta-ol-3,17-dione;6?-Hydroxy Androstenedione;6a-Hydroxy Androstenedione;Androst-4-ene-3,17-dione, 6alpha-hydroxy-;6.ALPHA.-OH-ADION;SCHEMBL10634877;DTXSID90550721;4-Androsten-6alpha-ol-3,17-dione;BDBM50523405;AKOS030241271;6.ALPHA.-HYDROXYANDROSTENEDIONE;6.ALPHA.-HYDROXY-ANDROSTENEDIONE;6alpha-hydroxyandrost-4-en-3,17-dione;6alpha-hydroxyandrost-4-ene-3,17-dione;6-OH-ANDROSTENEDIONE, (6.ALPHA.)-;NS00100925;ANDROST-4-EN-6.ALPHA.-OL-3,17-DIONE;6.ALPHA.-HYDROXY-4-ANDROSTENE-3,17-DIONE;6a-Hydroxy Androstenedione (1.0mg/ml in Methanol);Q27252873;(6.ALPHA.)-6-HYDROXYANDROST-4-ENE-3,17-DIONE;ANDROST-4-ENE-3,17-DIONE, 6.ALPHA.-HYDROXY-;(6S, 8R, 9S, 10R, 13S, 14S)-6-hydroxy-10, 13-dimethyl-2, 6, 7, 8, 9, 11, 12, 14, 15, 16-decahydro-1H-cyclopenta[a]phenanthrene-3, 17-dione

Suppliers and Price of 6alpha-Hydroxyandrostenedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 6alpha-Hydroxyandrostenedione

Chemical Property:

Melting Point:229-230 °C
Boiling Point:479.1±45.0 °C(Predicted)
PKA:14.03±0.60(Predicted)
PSA：54.37000
Density:1.19±0.1 g/cm3(Predicted)
LogP:3.05820
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:302.18819469
Heavy Atom Count:22
Complexity:577

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)CC(C4=CC(=O)CCC34C)O
Isomeric SMILES:C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)C[C@@H](C4=CC(=O)CC[C@]34C)O
Uses A metabolite of Androstenedione (A637550).

Technology Process of 6alpha-Hydroxyandrostenedione

There total 5 articles about 6alpha-Hydroxyandrostenedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.1%

: 63-05-8
Androstenedione

: 382-44-5
(8S,9S,10R,11S,13S,14S)-11-Hydroxy-10,13-dimethyl-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-3,17-dione

: 24704-84-5
6α-hydroxy-androst-4-ene-3,17-dione

: 564-33-0
11α-hydroxyandrost-4-ene-3,17-dione

Guidance literature:: With phosphate buffer; D-glucose; tieghemella orchidis; calcium chloride; In methanol; at 28 ℃; for 24h; Product distribution; other derivatives of androstene, other microbiological reagents, var reactions;
DOI:10.1007/BF00758303

Reference yield: 8.0%

: 53-43-0
dehydroepiandrosterone

: 24704-84-5
6α-hydroxy-androst-4-ene-3,17-dione

: 521-17-5,1963-03-7,4593-57-1,4593-58-2,14504-94-0,16895-59-3,47122-33-8,64162-67-0,75767-22-5,139973-51-6,151284-19-4
5-androstenediol

: 63-00-3
6β-hydroxy-4-androstene-3,17-dione

Guidance literature:: With Cladosporium sphaerospermum MRC 70266; In water; N,N-dimethyl-formamide; at 28 ℃; for 120h; Enzymatic reaction;
DOI:10.1080/10242422.2020.1844191

Reference yield: 4.0%

: 53-43-0
dehydroepiandrosterone

: 24704-84-5
6α-hydroxy-androst-4-ene-3,17-dione

: 2243-05-2
5α-androst-3,6,17-trione

: 2487-48-1,7522-54-5,62357-03-3,53-00-9
3β,7α-dihydroxyandrost-5-ene-17-one

: 2487-48-1
5-androsten-3β,7β-diol-17-one

: 62-84-0,31427-20-0
7α-hydroxyandrost-4-ene-3,17-dione

: 63-00-3
6β-hydroxy-4-androstene-3,17-dione

Guidance literature:: With Cladosporium sphaerospermum MRC 70266; In water; N,N-dimethyl-formamide; at 28 ℃; for 120h; Enzymatic reaction;
DOI:10.1080/10242422.2020.1844191