382-44-5 Usage
Uses
4-Androsten-11β-ol-3,17-dione is a steroid hormone. An analog of Androstenedione (A637550).
Biochem/physiol Actions
11β-Hydroxy-4-androstene-3,17-dione is a naturally occurring steroid that is primarily, if not strictly, produced in adrenal tissue. In diseases such as Cushing′s syndrome, adrenal-originated hyperandrogenism, and congenital adrenal hyperplasia, plasma 11β levels are very high. Plasma 11β concentration is very low in congenital 11-hydroxylase deficiency and adrenal insufficiency.
Check Digit Verification of cas no
The CAS Registry Mumber 382-44-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 382-44:
(5*3)+(4*8)+(3*2)+(2*4)+(1*4)=65
65 % 10 = 5
So 382-44-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h9,13-15,17,21H,3-8,10H2,1-2H3/t13-,14-,15-,17+,18-,19-/m0/s1
382-44-5Relevant articles and documents
Hydroxylation of androst-4-ene-3,17-dione with the aid of Curvularia lunata fungus
Shuvalova,Gabinskaya,Popova,Savinova,Andryushina
, p. 279 - 281 (2001)
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C-20 ketone reduction of hydrocortisone by rice field microalga Chlorella vulgaris MCCS 013
Ghasemi, Younes,Rasoul-Amini, Sara,Morowvat, Mohammad Hossein,Ghoshoon, Mohammad Bagher,Raee, Mohammad Javad,Khoubani, Soraya,Negintaji, Narges,Nouri, Fatemeh,Parvizi, Rezvan
experimental part, p. 824 - 828 (2010/08/19)
A unicellular microalga, Chlorella vulgaris, was isolated from rice field and applied in the biotransformation experiment of hydrocortisone (1). This strain has not been previously tested for hydrocortisone bioconversion. Fermentation was carried out in B
5β-cyano-substituted steroid compounds
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Table 36, (2008/06/13)
Novel 5β-cyano steroid compounds including compounds of Formula VII: wherein A—A, B—B, R3, R8and R9are as defined in the specification.