(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride

Base Information

Chemical Name:(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride
CAS No.:917836-01-2
Molecular Formula:C8H11ClN2O2
Molecular Weight:202.63814
Hs Code.:
Mol file:917836-01-2.mol

Synonyms:(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride;1-(2,3-dihydro(1,4)dioxino(2,3-c)pyridin-7-yl)MethaneaMine hydrochloride

Suppliers and Price of (2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride
50mg
$ 240.00

TRC
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride
10mg
$ 65.00

Matrix Scientific
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride 95%
500mg
$ 450.00

Matrix Scientific
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride 95%
1g
$ 725.00

Alichem
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride
1g
$ 602.08

AccelPharmtech
2,3-dihydro-1,4-Dioxino[2,3-c]pyridine-7-methanamine 97.00%
25G
$ 8510.00

AccelPharmtech
2,3-dihydro-1,4-Dioxino[2,3-c]pyridine-7-methanamine 97.00%
5G
$ 4530.00

AccelPharmtech
2,3-dihydro-1,4-Dioxino[2,3-c]pyridine-7-methanamine 97.00%
1G
$ 2640.00

Total 8 raw suppliers

Chemical Property of (2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride

Chemical Property:

Boiling Point:296.5±28.0 °C(Predicted)
PKA:7.54±0.29(Predicted)
PSA：57.37000
Density:1.263±0.06 g/cm3(Predicted)
LogP:1.01180

Purity/Quality:

97% ^*data from raw suppliers

(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanaminehydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride

There total 2 articles about (2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)MethanaMine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 917836-00-1
7-(azidomethyl)-2,3-dihydro-(1,4)dioxino(2,3-c)pyridine

: 917836-01-2
(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanamine

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 2h;

Reference yield:

: 443955-89-3
(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)-methanol

: 917836-01-2
(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanamine

Guidance literature:: Multi-step reaction with 2 steps

1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 3 h / 0 - 20 °C

2: hydrogen / palladium 10% on activated carbon / methanol / 2 h / 20 °C

With diphenyl phosphoryl azide; hydrogen; 1,8-diazabicyclo[5.4.0]undec-7-ene; palladium 10% on activated carbon; In methanol; toluene;

Reference yield:

: 917836-01-2
(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanamine

: 1073632-76-4
1,1-dimethylethyl (2,3-dihydro[1,4]dioxino[2,3-c]pyridin-7-ylmethyl){6-[(diphenylmethylidene)amino]-1,2,3,4-tetrahydro-2-naphthalenyl}carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tris(acetoxy)borohydride / methanol; chloroform / 16 h / 20 °C

2.1: sodium hydrogencarbonate / methanol / 0.17 h / 20 °C

2.2: 0 - 20 °C

3.1: sodium t-butanolate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl / toluene / 20 - 100 °C

With sodium tris(acetoxy)borohydride; sodium hydrogencarbonate; sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In methanol; chloroform; toluene;