2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine

Base Information

Chemical Name:2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine
CAS No.:1009378-52-2
Molecular Formula:C₁₀H₁₄BClN₂O₂
Molecular Weight:240.497
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40590536
Nikkaji Number:J3.624.063F
Wikidata:Q82484192
Mol file:1009378-52-2.mol

Synonyms:1009378-52-2;6-Chloropyrazine-2-boronic acid pinacol ester;2-CHLORO-6-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZINE;MFCD07367542;SCHEMBL1441832;DTXSID40590536;OBTWHVVHJBRISW-UHFFFAOYSA-N;2-CHLORO-6-(TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRAZINE;AKOS015947340;AB31184;PS-12973;SY356866;DB-058539;6-Boc-pyrazine-2-boronic Acid Pinacol Ester;EN300-1228878

Suppliers and Price of 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine 95+%
1g
$ 634.00

American Custom Chemicals Corporation
6-CHLOROPYRAZINE-2-BORONIC ACID PINACOL ESTER 95.00%
5MG
$ 502.87

Total 6 raw suppliers

Chemical Property of 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine

Chemical Property:

Boiling Point:334.5±42.0 °C(Predicted)
PKA:-0.93±0.10(Predicted)
PSA：44.24000
Density:1.19±0.1 g/cm3(Predicted)
LogP:1.42920
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:240.0836856
Heavy Atom Count:16
Complexity:260

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B1(OC(C(O1)(C)C)(C)C)C2=CN=CC(=N2)Cl

Technology Process of 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine

There total 2 articles about 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4774-14-5
2,6-dichloropyrazine

: 73183-34-3
bis(pinacol)diborane

: 1009378-52-2
2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine

Guidance literature:: With potassium acetate; tricyclohexylphosphine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 80 ℃; for 18h; Inert atmosphere;

Reference yield:

: 1009378-52-2
2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; for 4h; Inert atmosphere; Reflux;