4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine

Base Information

Chemical Name:4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine
CAS No.:1111638-16-4
Molecular Formula:C₁₀H₉F₂IN₄S
Molecular Weight:382.176
Hs Code.:
Mol file:1111638-16-4.mol

Synonyms:4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine;Pyrimidine,4-[1-(2,2-difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-

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Chemical Property of 4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine

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Technology Process of 4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine

There total 2 articles about 4-[1-(2,2-Difluoroethyl)-3-iodo-1H-pyrazol-4-yl]-2-(methylthio)-pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 598-39-0
1,1-difluoro-2-iodoethane

: 87199-17-5
4-formylphenylboronic acid,

: (R)-6-methoxy-4-(3-(quinoxaline-2-yloxy)pyrrolidine-1-yl)quinazoline-7-ol

: 1111638-74-4,1111637-86-5
4-(5-iodo-1H-pyrazol-4-yl)-2-(methylthio)pyrimidine

: 2-chloro-9-(4,4-difluoro-1-phenylbutyl)-9H-carbazole

: 4-(6,6-difluoro-1-phenylhex-1-yn-3-yl)-1,1′-biphenyl

: 2-(2,2-difluoroethyl)naphthalene

: 4-(2,2-difluoroethyl)benzaldehyde

: 1111638-16-4
4-(1-(2,2-difluoroethyl)-3-iodo-1H-pyrazol-4-yl)-2-(methylthio)pyrimidine

Guidance literature:: 3-iodo-1H-pyrazole; With sodium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; Inert atmosphere; Cooling with ice;

1,1-difluoro-2-iodoethane; In tetrahydrofuran; N,N-dimethyl-formamide; for 1.25h; Inert atmosphere;

Reference yield:

: 598-39-0
1,1-difluoro-2-iodoethane

: 87199-17-5
4-formylphenylboronic acid,

: (R)-6-methoxy-4-(3-(quinoxaline-2-yloxy)pyrrolidine-1-yl)quinazoline-7-ol

: 1111638-74-4,1111637-86-5
4-(5-iodo-1H-pyrazol-4-yl)-2-(methylthio)pyrimidine

: 2-chloro-9-(4,4-difluoro-1-phenylbutyl)-9H-carbazole

: 4-(6,6-difluoro-1-phenylhex-1-yn-3-yl)-1,1′-biphenyl

: 2-(2,2-difluoroethyl)naphthalene

: 4-(2,2-difluoroethyl)benzaldehyde

: 1111638-16-4
4-(1-(2,2-difluoroethyl)-3-iodo-1H-pyrazol-4-yl)-2-(methylthio)pyrimidine

: (R)-7-(2,2-difluoroethoxy)-6-methoxy-4-(3-(quinoxaline-2-yloxy)pyrrolidine-1-yl)quinazoline

Guidance literature:: 3-iodo-1H-pyrazole; With sodium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; Inert atmosphere; Cooling with ice;

1,1-difluoro-2-iodoethane; In tetrahydrofuran; N,N-dimethyl-formamide; for 1.25h; Inert atmosphere;