(R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid

Base Information

Chemical Name:(R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid
CAS No.:112229-51-3
Molecular Formula:C₁₃H₁₈N₂O₄
Molecular Weight:266.297
Hs Code.:
DSSTox Substance ID:DTXSID00427172

Synonyms:Z-D-Orn-OH;112229-51-3;(R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid;(2R)-5-amino-2-(phenylmethoxycarbonylamino)pentanoic acid;Cbz-Orn-OH;SCHEMBL2367228;DTXSID00427172;MFCD00237357;AKOS016844323;AS-82315;N~2~-[(Benzyloxy)carbonyl]-D-ornithine;N2-[(Phenylmethoxy)carbonyl]-D-ornithine;CS-0208698;F86536

Suppliers and Price of (R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 13 raw suppliers

Chemical Property of (R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid

Chemical Property:

XLogP3:-1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:266.12665706
Heavy Atom Count:19
Complexity:290

Purity/Quality:: >98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)NC(CCCN)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)COC(=O)N[C@H](CCCN)C(=O)O

Technology Process of (R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid

There total 1 articles about (R)-5-Amino-2-(((benzyloxy)carbonyl)amino)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 70-26-8,348-66-3,616-07-9,7006-33-9,25104-12-5,410523-47-6
L-ornithine

: 2640-58-6,112229-51-3
N²-benzyloxycarbonyl-L-ornithine

Guidance literature:: DOI:10.1055/s-1990-26840

Reference yield: 59.0%

: 540-88-5
acetic acid tert-butyl ester

: 2640-58-6,112229-51-3
N²-benzyloxycarbonyl-L-ornithine

: 26302-90-9
N²-benzyloxycarbonyl-L-ornithine tert-butyl ester

Guidance literature:: With perchloric acid; for 120h; Ambient temperature;
DOI:10.1055/s-1990-26840

Reference yield:

: 2640-58-6,112229-51-3
N²-benzyloxycarbonyl-L-ornithine

: 18928-01-3,37552-49-1,37552-50-4
N⁵-acetyl-N⁵-hydroxy-L-ornithine

Guidance literature:: Multi-step reaction with 5 steps

1: 59 percent / 72percent aq. HClO₄ / 120 h / Ambient temperature

2: 1) Na₂CO₃, 2) AcCl / 1) CH₂Cl₂, r.t., 3.5 h, 2) CH₂Cl₂, H₂O, r.t., 2 h

3: 90 percent / 10percent NH₃ in MeOH / 0.5 h / Ambient temperature

4: 90 percent / CF₃CO₂H / 0.5 h / Ambient temperature

5: 92 percent / H₂ / 5percent Pd-C / ethanol / 0.33 h / Ambient temperature

With perchloric acid; ammonia; hydrogen; sodium carbonate; acetyl chloride; trifluoroacetic acid; palladium on activated charcoal; In ethanol;
DOI:10.1055/s-1990-26840