1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester

Base Information

• Chemical Name: 1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester
• CAS No.: 1528-44-5
• Molecular Formula: C14H18O4
• Molecular Weight: 250.295
• Mol file: 1528-44-5.mol

Synonyms:1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester

Chemical Property of 1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester

Chemical Property:

• PSA: 52.60000
• LogP: 2.81700

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester

There total 3 articles about 1,3-Benzenedicarboxylic acid, bis(1-Methylethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

isophthalic acid (121-91-5) + isopropyl alcohol (67-63-0,8013-70-5) → diisopropyl isophthalate (1528-44-5)

Guidance literature:

With Oxone; In toluene; at 80 ℃; for 48h; Green chemistry;

DOI:10.1039/c8ob02539h

Reference yield: 47.0%

isophthalic acid (121-91-5) + isopropyl alcohol (67-63-0,8013-70-5) → diisopropyl isophthalate (1528-44-5) + 3-(isopropoxycarbonyl)benzoic acid (742101-35-5)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; at 65 ℃; for 44h;

DOI:10.1021/jm020839k

Reference yield:

→ diisopropyl isophthalate (1528-44-5)

Guidance literature:

Isophthaloylchlorid, sd. Isopropylalkohol;

upstream raw materials:

isophthalic acid

isopropyl alcohol

Downstream raw materials:

isophthalic acid

3-hydroxycarbonyl-propiophenone

N,N'-bis(2,2,6,6-tetramethyl-4-piperidinyl)-1,3-benzenedicarboxamide

Refernces

• 1、 Kahnberg, Pia,Lager, Erik,Rosenberg, Celia,Schougaard, Jette,Camet, Linda,Sterner, Olov,Nielsen, Elsebet ?stergaard,Nielsen, Mogens,Liljefors, Tommy. "Refinement and evaluation of a pharmacophore model for flavone derivatives binding to the benzodiazepine site of the GABAA receptor". . p. 4188 - 4201. Retrieved 2007/10/03.