Chemical Property of Hydrocortisone probutate
Chemical Property:
- Vapor Pressure:2.28E-17mmHg at 25°C
- Melting Point:122℃
- Boiling Point:608.9°C at 760 mmHg
- PKA:14.13±0.70(Predicted)
- Flash Point:194.7°C
- PSA：106.97000
- Density:1.20
- LogP:4.09350
- Storage Temp.:-20°C Freezer
- Solubility.:Chloroform (Sparingly), Methanol (Slightly)
- XLogP3:4.2
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:7
- Rotatable Bond Count:9
- Exact Mass:488.27740361
- Heavy Atom Count:35
- Complexity:938
- Purity/Quality:
-
97% *data from raw suppliers
Hydrocortisone17-Butyrate21-Propionate *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:CCCC(=O)OC1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)C(=O)COC(=O)CC
- Isomeric SMILES:CCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)CC
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Description
Hydrocortisone butyrate propionate is a potent, topical steroid reported to possess
minimal systemic side effects. It is indicated in the treatment of various acute
and chronic contact, eczematous, and atopic dermatoses and psoriasis.
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Uses
A synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agents. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.
