2-chloro-3-fluoro-6-hydroxybenzaldehyde

Base Information

Chemical Name:2-chloro-3-fluoro-6-hydroxybenzaldehyde
CAS No.:1263378-00-2
Molecular Formula:C7H4ClFO2
Molecular Weight:174.559
Hs Code.:
Mol file:1263378-00-2.mol

Synonyms:2-chloro-3-fluoro-6-hydroxybenzaldehyde

Suppliers and Price of 2-chloro-3-fluoro-6-hydroxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-chloro-3-fluoro-6-hydroxybenzaldehyde
10mg
$ 45.00

SynQuest Laboratories
2-Chloro-3-fluoro-6-hydroxybenzaldehyde 96%
1 g
$ 1195.00

SynQuest Laboratories
2-Chloro-3-fluoro-6-hydroxybenzaldehyde 96%
250 mg
$ 443.00

J&W Pharmlab
2-Chloro-3-fluoro-6-hydroxy-benzaldehyde 96%
50mg
$ 156.00

Crysdot
2-Chloro-3-fluoro-6-hydroxybenzaldehyde 95+%
1g
$ 518.00

Alichem
2-Chloro-3-fluoro-6-hydroxybenzaldehyde
1g
$ 451.54

Total 8 raw suppliers

Chemical Property of 2-chloro-3-fluoro-6-hydroxybenzaldehyde

Chemical Property:

Boiling Point:238.6±35.0 °C(Predicted)
PKA:7.24±0.23(Predicted)
PSA：37.30000
Density:1.508±0.06 g/cm3(Predicted)
LogP:1.99720

Purity/Quality:

97% ^*data from raw suppliers

2-chloro-3-fluoro-6-hydroxybenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-chloro-3-fluoro-6-hydroxybenzaldehyde

There total 6 articles about 2-chloro-3-fluoro-6-hydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1263378-40-0
2-chloro-3-fluoro-6-methoxy-benzaldehyde

: 1263378-00-2
2-chloro-3-fluoro-6-hydroxy-benzaldehyde

Guidance literature:: 2-chloro-3-fluoro-6-methoxy-benzaldehyde; With boron tribromide; In dichloromethane; at -78 - 20 ℃; for 17h; Inert atmosphere;

With methanol; In dichloromethane; at 0 - 20 ℃; for 0.833333h;

Reference yield: 78.3%

: 2-chloro-3-fluoro-6-(methoxymethoxy)benzaldehyde

: 1263378-00-2
2-chloro-3-fluoro-6-hydroxy-benzaldehyde

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 25 ℃; for 2h;

Reference yield:

: 202925-07-3
2-chloro-1-fluoro-4-methoxybenzene

: 1263378-00-2
2-chloro-3-fluoro-6-hydroxy-benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tert-butyl methyl ether; hexanes / 3 h / -78 °C

1.2: 0.75 h / -60 °C

2.1: boron tribromide / dichloromethane / 17 h / -78 - 20 °C / Inert atmosphere

2.2: 0.83 h / 0 - 20 °C

With n-butyllithium; boron tribromide; In hexanes; dichloromethane; tert-butyl methyl ether;