3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

Base Information

Chemical Name:3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid
CAS No.:678991-52-1
Molecular Formula:C₂₄H₂₀ClNO₄
Molecular Weight:421.88
Hs Code.:
DSSTox Substance ID:DTXSID20400760
Mol file:678991-52-1.mol

Synonyms:678991-52-1;3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid;2-Chloro-N-Fmoc-DL-phenylalanine;FMOC-D-2-CHLOROPHENYLALANINE;FMOC-2-CHLORO-DL-PHENYLALANINE;2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-chlorophenyl)propanoic acid;3-(2-CHLORO-PHENYL)-2-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPANOIC ACID;3-(2-chlorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid;N-Fmoc-2-chloro-L-phenylalanine;MFCD00797578;3-(2-chlorophenyl)-2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]propanoic acid;Fmoc-L-2-Chlorophenylalanine;SCHEMBL3728954;DTXSID20400760;AKOS030539504;AB06805;AB07180;SY023324;FT-0655084;FT-0656311;EN300-651008;F78749;A814011;A814677;F2147-6561;2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-chlorophenyl)propanoicacid

Suppliers and Price of 3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Activate Scientific
2-Chloro-N-Fmoc-DL-phenylalanine 95+%
1 g
$ 97.00

Activate Scientific
2-Chloro-N-Fmoc-DL-phenylalanine 95+%
25 g
$ 685.00

Acrotein
2-Chloro-N-Fmoc-DL-phenylalanine 97%
25g
$ 458.33

Total 7 raw suppliers

Chemical Property of 3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

Chemical Property:

PSA：75.63000
LogP:5.26530
XLogP3:5.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:421.1080858
Heavy Atom Count:30
Complexity:592

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-N-Fmoc-DL-phenylalanine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24)Cl

Technology Process of 3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid

There total 2 articles about 3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14091-11-3,80126-50-7
rac-2-chlorophenylalanine

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 198560-41-7,678991-52-1
3-(2-chloro-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid

Guidance literature:: With phosphate buffer; In N,N-dimethyl-formamide; at 0 ℃; for 24h; pH=9 - 10;
DOI:10.1021/ja0348391

Reference yield:

: 198560-41-7,678991-52-1
3-(2-chloro-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid

Guidance literature:

Reference yield:

: 198560-41-7,678991-52-1
(2S)-3-(2-chlorophenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid

: 29022-11-5
N-(fluoren-9-ylmethoxycarbonyl)glycine

: 35661-60-0
Fmoc-Leu-OH

: 71989-38-3,118488-18-9,204384-67-8
Fmoc-Tyr(tBu)-OH

: H-Tyr-Gly-Gly-(2-Cl)Phe-Leu-OH

Guidance literature:: Fmoc-Tyr(tBu)-OH; With benzotriazol-1-ol; diisopropyl-carbodiimide; In N,N-dimethyl-formamide;

With piperidine; In N,N-dimethyl-formamide;

N^α-Fmoc-Phe(2-Cl)-OH; N-(fluoren-9-ylmethoxycarbonyl)glycine; Fmoc-Leu-OH; Further stages;
DOI:10.1021/acsmedchemlett.5b00126